Detailed information of TA system TA170288

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 690171..690696
• Replicon: chromosome
• Accession: NZ_CP060396
• Organism: Synechococcus sp. CBW1006

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: H8F26_RS03270
• Protein ID: WP_197157427.1
• Coordinates: 690171..690452 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: H8F26_RS03275
• Protein ID: WP_197157429.1
• Coordinates: 690442..690696 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H8F26_RS03240	685304..685882	-	579	WP_197157417.1	hypothetical protein	-
H8F26_RS03245	685901..686182	-	282	WP_197157419.1	type II toxin-antitoxin system RelE/ParE family toxin	-
H8F26_RS03250	686172..686426	-	255	WP_197157421.1	hypothetical protein	-
H8F26_RS03255	687026..689359	-	2334	WP_197158944.1	DEAD/DEAH box helicase	-
H8F26_RS03260	689430..689777	-	348	WP_197157423.1	type II toxin-antitoxin system PemK/MazF family toxin	-
H8F26_RS03265	689777..690094	-	318	WP_197157425.1	ribbon-helix-helix protein, CopG family	-
H8F26_RS03270	690171..690452	-	282	WP_197157427.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H8F26_RS03275	690442..690696	-	255	WP_197157429.1	plasmid stabilization protein	Antitoxin
H8F26_RS03280	691052..693418	-	2367	WP_197158945.1	DEAD/DEAH box helicase	-
H8F26_RS03285	693487..693678	-	192	WP_197157431.1	type II toxin-antitoxin system RelE/ParE family toxin	-
H8F26_RS03290	693979..694314	+	336	WP_197157433.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
H8F26_RS03295	694328..694690	+	363	WP_197157435.1	type II toxin-antitoxin system VapC family toxin	-
H8F26_RS03300	694853..695263	+	411	WP_197157437.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10934.72 Da
• Isoelectric Point: 11.2551

>T170288 WP_197157427.1 NZ_CP060396:c690452-690171 [Synechococcus sp. CBW1006]
MLFELAFHPEALREWRKLTPGIREQFRNKLAGRLTEPRIPASKLRGSSNRYKIKLRAAGYRLVYEVRDHELLVLVVAVGK
REHNVVDQRADQR

Nucleotide

• Length: 282 bp

>T170288 NZ_CP077262:c122589-122215 [Citrobacter pasteurii]
ATGGTCAAAGGATCCGCGCTTTTTGATACCAACATCCTCATCGACCTGTTTAGTGGACGGAGTGAAGCAAAGCAAGCGAT
AGAAACATGGCCGCCGCAGAATGCGATCAGCCTTATCACCTGGATGGAAGTGATGGTTGGGGCAAAGAAATACCATCAGG
AATCCTGCACACGCGTTGCGTTGAGCGCTTTTAACGTGATCGGTGTTTCACAGGATATTGCTGAACGAAGCGTGAGTATC
AGGCAGGAATATGGGATGAAATTGCCGGATGCCATTATTCTGGCAACAGCACAGATTCATCGTCTTACGCTGGTTACGCG
AAATACTAAGGATTTTGCAGGCCTATCCGGTGTGGTCACACCGTATACATTATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9124.41 Da
• Isoelectric Point: 4.4341

>AT170288 WP_197157429.1 NZ_CP060396:c690696-690442 [Synechococcus sp. CBW1006]
MAHRVLTETAVSISEHKKNPMATVAAGEGMAVAVLNRNEPAFYCVPARAYEELMDLVDDLELGRIADARLTDGQEPVRVS
LDAL

Nucleotide

• Length: 255 bp

>AT170288 NZ_CP077262:c122831-122589 [Citrobacter pasteurii]
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGACGAAGTGATTAAACGTCTTGATGACCTCAAGGT
GCAGCGTAACCTGCCGCGAGCTGAACTCTTGCGGGAGGCCGTTGAGCAGTATCTGGAAAGGCAGGAACAGGCTGAAACGA
CTATTTCCAGCGCTCTCGGACTCTGGAAAGGTTGTGAAGAAGATGGCGTTGAGTACCAACGCAAACTTCGTGAGGAATGG
TAA