Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 690171..690696 Replicon chromosome
Accession NZ_CP060396
Organism Synechococcus sp. CBW1006

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H8F26_RS03270 Protein ID WP_197157427.1
Coordinates 690171..690452 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H8F26_RS03275 Protein ID WP_197157429.1
Coordinates 690442..690696 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8F26_RS03240 685304..685882 - 579 WP_197157417.1 hypothetical protein -
H8F26_RS03245 685901..686182 - 282 WP_197157419.1 type II toxin-antitoxin system RelE/ParE family toxin -
H8F26_RS03250 686172..686426 - 255 WP_197157421.1 hypothetical protein -
H8F26_RS03255 687026..689359 - 2334 WP_197158944.1 DEAD/DEAH box helicase -
H8F26_RS03260 689430..689777 - 348 WP_197157423.1 type II toxin-antitoxin system PemK/MazF family toxin -
H8F26_RS03265 689777..690094 - 318 WP_197157425.1 ribbon-helix-helix protein, CopG family -
H8F26_RS03270 690171..690452 - 282 WP_197157427.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H8F26_RS03275 690442..690696 - 255 WP_197157429.1 plasmid stabilization protein Antitoxin
H8F26_RS03280 691052..693418 - 2367 WP_197158945.1 DEAD/DEAH box helicase -
H8F26_RS03285 693487..693678 - 192 WP_197157431.1 type II toxin-antitoxin system RelE/ParE family toxin -
H8F26_RS03290 693979..694314 + 336 WP_197157433.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
H8F26_RS03295 694328..694690 + 363 WP_197157435.1 type II toxin-antitoxin system VapC family toxin -
H8F26_RS03300 694853..695263 + 411 WP_197157437.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10934.72 Da        Isoelectric Point: 11.2551

>T170288 WP_197157427.1 NZ_CP060396:c690452-690171 [Synechococcus sp. CBW1006]
MLFELAFHPEALREWRKLTPGIREQFRNKLAGRLTEPRIPASKLRGSSNRYKIKLRAAGYRLVYEVRDHELLVLVVAVGK
REHNVVDQRADQR

Download         Length: 282 bp

>T170288 NZ_CP077262:c122589-122215 [Citrobacter pasteurii]
ATGGTCAAAGGATCCGCGCTTTTTGATACCAACATCCTCATCGACCTGTTTAGTGGACGGAGTGAAGCAAAGCAAGCGAT
AGAAACATGGCCGCCGCAGAATGCGATCAGCCTTATCACCTGGATGGAAGTGATGGTTGGGGCAAAGAAATACCATCAGG
AATCCTGCACACGCGTTGCGTTGAGCGCTTTTAACGTGATCGGTGTTTCACAGGATATTGCTGAACGAAGCGTGAGTATC
AGGCAGGAATATGGGATGAAATTGCCGGATGCCATTATTCTGGCAACAGCACAGATTCATCGTCTTACGCTGGTTACGCG
AAATACTAAGGATTTTGCAGGCCTATCCGGTGTGGTCACACCGTATACATTATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9124.41 Da        Isoelectric Point: 4.4341

>AT170288 WP_197157429.1 NZ_CP060396:c690696-690442 [Synechococcus sp. CBW1006]
MAHRVLTETAVSISEHKKNPMATVAAGEGMAVAVLNRNEPAFYCVPARAYEELMDLVDDLELGRIADARLTDGQEPVRVS
LDAL

Download         Length: 255 bp

>AT170288 NZ_CP077262:c122831-122589 [Citrobacter pasteurii]
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGACGAAGTGATTAAACGTCTTGATGACCTCAAGGT
GCAGCGTAACCTGCCGCGAGCTGAACTCTTGCGGGAGGCCGTTGAGCAGTATCTGGAAAGGCAGGAACAGGCTGAAACGA
CTATTTCCAGCGCTCTCGGACTCTGGAAAGGTTGTGAAGAAGATGGCGTTGAGTACCAACGCAAACTTCGTGAGGAATGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References