Detailed information of TA system TA170287

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 685901..686426
• Replicon: chromosome
• Accession: NZ_CP060396
• Organism: Synechococcus sp. CBW1006

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: H8F26_RS03245
• Protein ID: WP_197157419.1
• Coordinates: 685901..686182 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: H8F26_RS03250
• Protein ID: WP_197157421.1
• Coordinates: 686172..686426 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H8F26_RS03210	682095..682721	-	627	Protein_631	IS630 family transposase	-
H8F26_RS03215	683079..683324	+	246	WP_197157408.1	hypothetical protein	-
H8F26_RS03220	683382..684065	+	684	WP_197157410.1	cupin domain-containing protein	-
H8F26_RS03225	684075..684494	-	420	WP_197157412.1	nuclear transport factor 2 family protein	-
H8F26_RS03230	684541..684957	-	417	WP_197157413.1	hypothetical protein	-
H8F26_RS03235	685026..685190	-	165	WP_197157415.1	hypothetical protein	-
H8F26_RS03240	685304..685882	-	579	WP_197157417.1	hypothetical protein	-
H8F26_RS03245	685901..686182	-	282	WP_197157419.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H8F26_RS03250	686172..686426	-	255	WP_197157421.1	hypothetical protein	Antitoxin
H8F26_RS03255	687026..689359	-	2334	WP_197158944.1	DEAD/DEAH box helicase	-
H8F26_RS03260	689430..689777	-	348	WP_197157423.1	type II toxin-antitoxin system PemK/MazF family toxin	-
H8F26_RS03265	689777..690094	-	318	WP_197157425.1	ribbon-helix-helix protein, CopG family	-
H8F26_RS03270	690171..690452	-	282	WP_197157427.1	type II toxin-antitoxin system RelE/ParE family toxin	-
H8F26_RS03275	690442..690696	-	255	WP_197157429.1	plasmid stabilization protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	682257..682784	527

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11032.82 Da
• Isoelectric Point: 10.9300

>T170287 WP_197157419.1 NZ_CP060396:c686182-685901 [Synechococcus sp. CBW1006]
MPFELAFHPEDLREWRQLSAGIREQFKKKLAERLVVPRIPASKLRDSSDRYKIKLRSAGFRLVYEVRDHEVLVLVVAVGK
RERNAVYRQADQR

Nucleotide

• Length: 282 bp

>T170287 NZ_CP077260:c4449758-4449369 [Providencia rettgeri]
GTGGCGTTCTATAAAATTTCCTCATTTAAGCGAAGCACCAAAAAAATTAAGATAATGGATAAACACTTGCTTAAGGCTGC
AAATGAAGTCTTAGCGGGGGTTTATGAAGCAGACTTAGGAAGTGGTGTAATTAAAAAAAGGATTGCCATTAATGGAAAAG
GGAAAAGTGGTGGGGGCAGGGTTATTATATTCTTCAAAGTTAGCCATCATCTCTTTTTTGCCGATGGTTGGGAGAAATGC
AATATAGCTGCTAAAGGAGTAAAAGAAATTGAAGATGATGAACTAGATGCGTATAAGAATTTATCTCGACTTTTTCTTAA
TTATACGGATGATAAAATTGCTGATTTAGTTTTACATAATATTTTGGAGGAGCTTACTGATGAGCAATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9122.43 Da
• Isoelectric Point: 4.4341

>AT170287 WP_197157421.1 NZ_CP060396:c686426-686172 [Synechococcus sp. CBW1006]
MVHRVLAETAVSISEHKKNPMATVAAGEGMAVAVLNRNEPAFYCVPARAYEELMDLVDDLELGRLADARLTDGQEPVRVS
LDAL

Nucleotide

• Length: 255 bp

>AT170287 NZ_CP077260:c4449379-4449050 [Providencia rettgeri]
ATGAGCAATAAACTAGAAAACATGCTTGAGCTAGCGAAAGAGTTACATCAGGTTGATGCTGCACCAAAAAGTTTAGTTAC
TGATTTAGAACAGAAGGTTGGAAATCGTAAAATAAATAATAAAATCAAGGTAGTACCTATGATGAGCGGTGCGCAAATCA
AACAACTCCGTGCTCAATATGGAATGTCACAAGCCATGTTAGCTTTAGCGCTGGGCATGTCTAAGGAAAGCGTATCTAAG
TGGGAAAGAGAAGAAAAAAAACCCAGTGGCCCAGCTCTAAGAATGCTACATCTTATAGAGCAGCGAGGGCCAGAGATTTT
AATTATTTAA