Detailed information of TA system TA170279

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-stbD/ParE-YafN
• Location: 1395625..1396147
• Replicon: chromosome
• Accession: NZ_CP060395
• Organism: Synechococcus sp. CBW1108

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: H8F27_RS07435
• Protein ID: WP_197152769.1
• Coordinates: 1395625..1395903 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: H8F27_RS07440
• Protein ID: WP_197152775.1
• Coordinates: 1395893..1396147 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H8F27_RS07425	1391606..1392685	-	1080	WP_197147936.1	photosystem II q(b) protein	-
H8F27_RS07430	1393221..1395590	-	2370	WP_197153427.1	DEAD/DEAH box helicase	-
H8F27_RS07435	1395625..1395903	-	279	WP_197152769.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H8F27_RS07440	1395893..1396147	-	255	WP_197152775.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
H8F27_RS07445	1397135..1397647	+	513	WP_197152782.1	hypothetical protein	-
H8F27_RS07450	1397661..1398482	-	822	WP_197153428.1	formylglycine-generating enzyme family protein	-
H8F27_RS07455	1398666..1400531	+	1866	WP_197152786.1	sulfatase-like hydrolase/transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10731.68 Da
• Isoelectric Point: 11.1218

>T170279 WP_197152769.1 NZ_CP060395:c1395903-1395625 [Synechococcus sp. CBW1108]
MSYELAFHPEALREWRTLSAGIREQFKKKLAERLIEPRIPASKLRGSSHRYKIKLRAAGFRLVYEVRDCEVLVLVVAVGK
RERMTHGRLQAL

Nucleotide

• Length: 279 bp

>T170279 NZ_CP077259:1414148-1414918 [Streptococcus mitis]
GTGGAAATCCAAGATTATACTGATAGTGAATTCAAACATGCTTTAGAGCGGAATCTTCGTTCTCTGACAAGAGGAAAAAA
GTCCAGTAAGCAACCTATAGCGATTTTACTTGGAGGACAAAGTGGTGCTGGTAAGACTACAATTCATCGTATTAAACAGA
AAGAATTTCAAGGAAATATTGTTATCATAGATGGCGATAGTTTTCGCTCTCAACATCCACACTATTTAGAACTGCAGCAA
GAATATGGCAAAGACAGTGTAGAATACACCAAAGATTTTGCAGGAAAAATGGTAGAGTCTTTAGTAAGAGAATTGAGTCA
TTTGGGATACAATCTTTTGATAGAGGGAACTTTACGAACGATTGATGTTCCAAAGAAAACAGCAAAACTCTTGAAAAATA
AGGGGTATGAGGTACAATTAGCCTTAATTGCGACAAAGCCTAAGCTGTCCTATCTGAGTACTCTTATCCGATACGAAGAA
CTGTACGCTATCAATCCAAATCAAGCACGCGCAACTCCAAAAGAACATCATGATTTCATTGTAAATCATCTAGTTGATAA
TACACGGCAATCGGAAGAACTAGCTATCTTTGAAAGAATTCAAATTTATCAACGAGATAGAAGTTGTGTATATGATTCAG
GAGAAGATAAAACTTCAGCAGCAACCGTCCTTCATGATTTACTATTTGGAGAATGGAATCAAGTTGAGAAAGAGATGCTT
AAATCTGGAGAAGAAAGATTGAAAGATTTAACGAATCGAAATGATTGTTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9152.46 Da
• Isoelectric Point: 4.3557

>AT170279 WP_197152775.1 NZ_CP060395:c1396147-1395893 [Synechococcus sp. CBW1108]
MAHRVLTETAVSISEHKKNPMATVAAGEGMAVAVLNRNEPAFYCVPAKAYEELMDLVEDLELGRIADARLADGQEPLRVS
LDEL

Nucleotide

• Length: 255 bp

>AT170279 NZ_CP077259:1413672-1414148 [Streptococcus mitis]
ATGATTGGAAAGAACATAAAATCCTTACGTAAAACACATGACTTAACACAACCCGAATTTGCCCAAATTATAGGAATTTC
TCGCAATAGCTTGAGTCGTTATGAAAATGGAACTAGTCCAGTCTCTACGGAACTAATAGATATCATTTGTCAGAAGTTTA
ATGTATCTTATGTCGATATTGTAGGAGAAGATAAAATGCTCAATCCTGTTGAAGATTATGAATTGACTTTAAAAATTGAA
ATTGTGAAAGAAAGAGGAGCTAATCTATTATCACGACTCTATCGTTATCAAGATAGTCAGGGAATTAGCATTGATGATGA
ATCTAATCCTTGGATTTTAATGAGTGATGATCTTTCTGATTTGATTCATACGAATATCTATCTAGTTGAAACTTTTGATG
AAATAGAGAGATATAGCGGCTATTTGGATGGAATTGAACGTATGTTAGAGATATCTGAAAAACGGATGGTAGCCTAG