Detailed information of TA system TA170276

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 972732..973429
• Replicon: chromosome
• Accession: NZ_CP060395
• Organism: Synechococcus sp. CBW1108

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: H8F27_RS05240
• Protein ID: WP_197151847.1
• Coordinates: 972732..973160 (-)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: H8F27_RS05245
• Protein ID: WP_197151849.1
• Coordinates: 973169..973429 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H8F27_RS05225	969415..969804	+	390	WP_197151831.1	phosphatase PAP2 family protein	-
H8F27_RS05230	969736..970395	-	660	WP_197151838.1	phosphatase PAP2 family protein	-
H8F27_RS05235	970741..972309	-	1569	WP_197148269.1	IS5 family transposase	-
H8F27_RS05240	972732..973160	-	429	WP_197151847.1	PIN domain-containing protein	Toxin
H8F27_RS05245	973169..973429	-	261	WP_197151849.1	hypothetical protein	Antitoxin
H8F27_RS05250	973467..974915	-	1449	WP_197151851.1	DNA repair protein RadA	-
H8F27_RS05255	975036..975806	+	771	WP_197151853.1	response regulator transcription factor	-
H8F27_RS05260	975787..977097	+	1311	WP_197153380.1	phosphate acyltransferase PlsX	-
H8F27_RS05265	977177..978181	+	1005	WP_197153381.1	ketoacyl-ACP synthase III	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain toxin (2-141)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15638.00 Da
• Isoelectric Point: 6.4748

>T170276 WP_197151847.1 NZ_CP060395:c973160-972732 [Synechococcus sp. CBW1108]
VCVDVNVLVQACLQISPRHHEARAWLLANRAVPEGLGLFSVVVSGFLRVATDRRVFSEPLDAAVAIAFIDSLTASPAVSI
LDPGPRHWDLFRQMVLDHRPSSQDMTDVYLAAAALEIGATWVSFDRGFARFKGLRWLNPADL

Nucleotide

• Length: 429 bp

>T170276 NZ_CP077248:c1780795-1780028 [Streptococcus gordonii]
ATGAAACTAGAAGAATTTAGTCAAGATGATTTTGAACGAGCATCCAGACGACTCGTTCGTTCTTTAACTCGTGGTAAAAC
AACTTCGTCTCAGCCCAAGGCTATCTTGCTAGGTGGACAGAGTGGTGCTGGGAAAACAACGATTCATCGTATTAAACAAA
GGGAATTTCAAGGTAATATCATTATCATTGATGGAGATAGTTATCGCTCTTTTCATCCGAACTACCTTGGCTTACAGGAA
AAGTATGGAAAAGATAGTGTGGATTATACCAAAGTATTCGCGGGACAAATGGTTGAATATCTCGTAGATGAATTGAGTAA
ACAAGGTTATCATTTGTTAATCGAGGGCACCTTGAGAACAACAGAAGTTCCTAGAAAAACGGCACAATTATTGATAACTA
AAGGATATCAAGTCTCACTTGCACTAATAGCGACCAAGCCAGAATTGTCCTATCTCAGTACTTTGATACGTTATGAGGAG
CTCTACGCCATAGATTCTAGTCAAGCTAGAGCAACTCCTAAAGCACACCATGATGGAATTGTAGAACATATGGTTGATAA
CTTACGGGAGTTAGAAAATGATAAACTTTTTAGACAAATTCAAATTTATCAAAGAGATCAATCGTGTGTTTATGATTCGC
AAGTAGATCAAATCTCAGCAGCAGAAGTTCTACAAGAATGCCTATTTGGAAAATGGAGTAAGGTGGAGGAAGAGATGTTG
AAGTTGGGACAGGAACGGTTGAGAGAGATGGGGGGAATTAATAAGTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9224.61 Da
• Isoelectric Point: 5.0022

>AT170276 WP_197151849.1 NZ_CP060395:c973429-973169 [Synechococcus sp. CBW1108]
MRTTLTISDALYVQAKLQAAREGASVGAVFEAALQAYLDRARQLARSELPPLPVHGGGVLRPGVDLDDMSALRALLDEGL
PLEQLR

Nucleotide

• Length: 261 bp

>AT170276 NZ_CP077248:c1781271-1780795 [Streptococcus gordonii]
ATGATAGGAGAAAATATTAAAGCGTTACGTAAAACACATGATCTAACCCAGCCTGAGTTCGCAAAGATTGTTGGTATCTC
TCGAAATAGCCTAAGTCGTTATGAAAACGGGACAAGTTCAATTTCGACAGAATTAATAGATCGTATTTGTCAGAAATTTA
ATGTTTCCTATATCGATATTGTAGGAGAGGAAAAGATGCTCACGCCAGTGGAAGATTACCAGCTCACTCTGAAAATTGAA
GTGATTAAAGAACGAGGGGCGAATATCTTAGCGCAACTTTATCGTTTTCAAGATGAACAAGGAATTGCATTTGATGATAC
TTCTAATCCTTGGGTTCTAATGAGCGATGATTTGTCTGATTTGCTGAACACGAAGATTTATCTTGTGGGGACTTTTGATG
AAGTAGAGCGATATAATGGCTATTTGGATGGCATTGAACGGATGCTAGAACAAGCTACTCATCTGGTGGTGGCTTAA