Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 6028384..6029039 Replicon chromosome
Accession NZ_CP060394
Organism Acidobacterium sp. 4Y35

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H7849_RS25390 Protein ID WP_186743234.1
Coordinates 6028650..6029039 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H7849_RS25385 Protein ID WP_186743233.1
Coordinates 6028384..6028650 (+) Length 89 a.a.

Genomic Context

H7849_RS25370H7849_RS25375H7849_RS25380H7849_RS25385H7849_RS25390H7849_RS25395H7849_RS25405H7849_RS25410H7849_RS25360H7849_RS25365H7849_RS25400
Location: 6025300..6025788 (489 bp)
Type: Others
Protein ID: WP_186743230.1
Location: 6025844..6027418 (1575 bp)
Type: Others
Protein ID: WP_186743231.1
Location: 6027802..6028263 (462 bp)
Type: Others
Protein ID: WP_186743232.1
Location: 6028384..6028650 (267 bp)
Type: Antitoxin
Protein ID: WP_186743233.1
Location: 6028650..6029039 (390 bp)
Type: Toxin
Protein ID: WP_186743234.1
Location: 6029165..6029923 (759 bp)
Type: Others
Protein ID: WP_186743235.1
Location: 6031446..6032528 (1083 bp)
Type: Others
Protein ID: WP_186743236.1
Location: 6032525..6033739 (1215 bp)
Type: Others
Protein ID: WP_186743237.1
Location: 6023505..6024758 (1254 bp)
Type: Others
Protein ID: WP_186743228.1
Location: 6024919..6025218 (300 bp)
Type: Others
Protein ID: WP_186743229.1
Location: 6030231..6031214 (984 bp)
Type: Others
Protein ID: WP_186747875.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H7849_RS253606023505..6024758-1254WP_186743228.1glucose-1-phosphate adenylyltransferase-
H7849_RS253656024919..6025218-300WP_186743229.1hypothetical protein-
H7849_RS253706025300..6025788+489WP_186743230.1hypothetical protein-
H7849_RS253756025844..6027418+1575WP_186743231.1methylmalonyl-CoA mutase-
H7849_RS253806027802..6028263+462WP_186743232.1hypothetical protein-
H7849_RS253856028384..6028650+267WP_186743233.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
H7849_RS253906028650..6029039+390WP_186743234.1type II toxin-antitoxin system VapC family toxinToxin
H7849_RS253956029165..6029923+759WP_186743235.1TIGR00266 family protein-
H7849_RS254006030231..6031214-984WP_186747875.1ROK family protein-
H7849_RS254056031446..6032528+1083WP_186743236.1FtsQ-type POTRA domain-containing protein-
H7849_RS254106032525..6033739+1215WP_186743237.1cell division protein FtsA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(2-87)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14316.52 Da        Isoelectric Point: 7.8568

>T170273 WP_186743234.1 NZ_CP060394:6028650-6029039 [Acidobacterium sp. 4Y35]
MVLDTSAILAVLLEEPEAAQLVHFIGEDRIRLCSAVSFVEASIVLRNRKGERGRQKLDQFLRRARVQITAVDVKQAEVAR
EAYEKFGKGKHPAGLNLGDCFSYALAKTTNEPLLFKGEDFVKTDVVSVP

Download         Length: 390 bp

>T170273 NZ_CP077242:3377195-3377449 [Escherichia fergusonii]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACTCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9673.99 Da        Isoelectric Point: 5.7121

>AT170273 WP_186743233.1 NZ_CP060394:6028384-6028650 [Acidobacterium sp. 4Y35]
VPLYIKNPNVEKSARRLARLTGETLTEATERAIEERLARLRPAQSPAHGATQLEKDLLRIAHQCAALPDVDTRMADEILG
YDAEGLPG

Download         Length: 267 bp

>AT170273 NZ_CP077242:3376947-3377198 [Escherichia fergusonii]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAACGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCCCTGGAAGAGACGGCTTATC
TATTGCGTTCCCCCGCTAATGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References