170261

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB-DinJ
Location 2194..2810 Replicon plasmid pPsychbacter006
Accession NZ_CP060391
Organism Psychrobacter sp. KCTC 72983

Toxin (Protein)


Gene name relE Uniprot ID A0A1G6ZZT1
Locus tag PSBA01_RS12960 Protein ID WP_025652647.1
Coordinates 2520..2810 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1G7A1Y7
Locus tag PSBA01_RS12955 Protein ID WP_025652648.1
Coordinates 2194..2427 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSBA01_RS12940 120..461 + 342 WP_025652650.1 hypothetical protein -
PSBA01_RS12945 660..830 + 171 WP_156410067.1 hypothetical protein -
PSBA01_RS12950 1157..2113 + 957 WP_025652649.1 replication initiation protein -
PSBA01_RS12955 2194..2427 + 234 WP_025652648.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PSBA01_RS12960 2520..2810 + 291 WP_025652647.1 type II toxin-antitoxin system prevent-host-death family antitoxin Toxin
PSBA01_RS12965 2807..3061 + 255 WP_025652646.1 Txe/YoeB family addiction module toxin -
PSBA01_RS12970 3322..4398 - 1077 WP_101211256.1 transposase -
PSBA01_RS12975 4922..5890 + 969 WP_025652670.1 DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..49070 49070


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-54)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10852.26 Da        Isoelectric Point: 4.8780

>T170261 WP_025652647.1 NZ_CP060391:2520-2810 [Psychrobacter sp. KCTC 72983]
MDVVNYTDFRKGLAKYIDKVDTDKSPIVITRQNAKPAVLMSLEEFNSYEETLHLLKSPTNAKRLRRSIADAKAGRLIEHD
INTDDALLTCDDEVDA

Download         Length: 291 bp

>T170261 NZ_CP077242:c443626-443324 [Escherichia fergusonii]
ATGGCTCAAAAGAATAATATAAGGAGTTTTCGTGATGCCTGGCTGGCTGATTTTTTTGTCCACTCAACGCCACATAGAAA
GATTCCTGCTGAAATCCATACCACATTATCAAGAAAATTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATATTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTATTTAGATCCACACAACTACTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8556.52 Da        Isoelectric Point: 7.0026

>AT170261 WP_025652648.1 NZ_CP060391:2194-2427 [Psychrobacter sp. KCTC 72983]
MTTTNYNIRLDQELKDSAFAVFESYGLTPSQAIKLFLTQVAQTNTVPLSFDYQKPSNLNTPPQTSAGDYGLSGQRHK

Download         Length: 234 bp

>AT170261 NZ_CP077242:c443288-442947 [Escherichia fergusonii]
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAGCCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACAACTG
AAATGGCGTTTCGTCTGGCTAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCGGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACACAAGAAGAATTGGGACGGATTGAAACAGTGGCTGACTATTTGGCTCGCCGTGAAGA
GCGTGCAAAGAATGTTGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1G6ZZT1

Antitoxin

Source ID Structure
AlphaFold DB A0A1G7A1Y7

References