Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1110445..1111244 Replicon chromosome
Accession NZ_CP060388
Organism Sphingobium sp. KCTC 72723

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag SPBM01_RS05500 Protein ID WP_188064359.1
Coordinates 1110741..1111244 (+) Length 168 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID N1MNI2
Locus tag SPBM01_RS05495 Protein ID WP_006960007.1
Coordinates 1110445..1110732 (+) Length 96 a.a.

Genomic Context

SPBM01_RS05485SPBM01_RS05495SPBM01_RS05500SPBM01_RS05505SPBM01_RS05510SPBM01_RS05515SPBM01_RS05490
Location: 1105977..1109720 (3744 bp)
Type: Others
Protein ID: WP_188064357.1
Location: 1110445..1110732 (288 bp)
Type: Antitoxin
Protein ID: WP_006960007.1
Location: 1110741..1111244 (504 bp)
Type: Toxin
Protein ID: WP_188064359.1
Location: 1111271..1112185 (915 bp)
Type: Others
Protein ID: WP_188064360.1
Location: 1112567..1114315 (1749 bp)
Type: Others
Protein ID: WP_188064361.1
Location: 1114312..1114938 (627 bp)
Type: Others
Protein ID: WP_188064362.1
Location: 1109717..1110250 (534 bp)
Type: Others
Protein ID: WP_188064358.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SPBM01_RS054851105977..1109720+3744WP_188064357.1conjugal transfer protein TraG N-terminal domain-containing protein-
SPBM01_RS054901109717..1110250-534WP_188064358.1hypothetical protein-
SPBM01_RS054951110445..1110732+288WP_006960007.1DUF1778 domain-containing proteinAntitoxin
SPBM01_RS055001110741..1111244+504WP_188064359.1GNAT family N-acetyltransferaseToxin
SPBM01_RS055051111271..1112185+915WP_188064360.1HEPN domain-containing protein-
SPBM01_RS055101112567..1114315+1749WP_188064361.1SIR2 family protein-
SPBM01_RS055151114312..1114938+627WP_188064362.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-144)

Antitoxin

Vibrio phage ICP1, Orf50

(4-92)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18421.94 Da        Isoelectric Point: 8.9296

>T170256 WP_188064359.1 NZ_CP060388:1110741-1111244 [Sphingobium sp. KCTC 72723]
MAPQFRIEKLRRDHAIDVFDCGREELNRFLSRYAWQAQQGGASQSYVALTGDEVVGFHTLVVGHVDHSDAPDRLTKGMAR
HPVPLMILARLGVSTGYQGKGLGSGLLKDALTRTLQAADIAGIRAIAAHAKDEAARQFYQNFDFIPGLSDPNHMFLLSKD
ARRHLQG

Download         Length: 504 bp

>T170256 NZ_CP077238:c2104517-2104335 [Acinetobacter pittii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10466.82 Da        Isoelectric Point: 5.7066

>AT170256 WP_006960007.1 NZ_CP060388:1110445-1110732 [Sphingobium sp. KCTC 72723]
MASATARTEKLDLRLSPTAKRTLQQAALAAHRSVSEFVLESALARAEETLPDRREFNLDADQWAAFLAALDAPPRHTPRL
AELLTKPSVFEQDPG

Download         Length: 288 bp

>AT170256 NZ_CP077238:c2104242-2103838 [Acinetobacter pittii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBN1MNI2

References