170255

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 367422..367975 Replicon chromosome
Accession NZ_CP060388
Organism Sphingobium sp. KCTC 72723

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SPBM01_RS01980 Protein ID WP_188063773.1
Coordinates 367652..367975 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SPBM01_RS01975 Protein ID WP_188063772.1
Coordinates 367422..367655 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SPBM01_RS01940 363301..364050 + 750 WP_188062383.1 electron transfer flavoprotein subunit beta/FixA family protein -
SPBM01_RS01945 364047..364976 + 930 WP_188063766.1 FAD-binding protein -
SPBM01_RS01950 365044..365247 - 204 WP_188063767.1 hypothetical protein -
SPBM01_RS01955 365351..365551 - 201 WP_188063768.1 hypothetical protein -
SPBM01_RS01960 365631..365846 - 216 WP_188063769.1 cold-shock protein -
SPBM01_RS01965 366039..367091 - 1053 WP_188063770.1 hypothetical protein -
SPBM01_RS01970 367175..367375 - 201 WP_188063771.1 addiction module antitoxin -
SPBM01_RS01975 367422..367655 + 234 WP_188063772.1 DUF433 domain-containing protein Antitoxin
SPBM01_RS01980 367652..367975 + 324 WP_188063773.1 DUF5615 family PIN-like protein Toxin
SPBM01_RS01985 368056..368928 + 873 WP_188063774.1 FRG domain-containing protein -
SPBM01_RS01990 368934..371852 - 2919 WP_188063775.1 excinuclease ABC subunit UvrA -
SPBM01_RS01995 371982..372131 - 150 WP_188063776.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 314140..408045 93905


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-74)

Antitoxin

Protein of unknown function DUF433

(9-64)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11928.88 Da        Isoelectric Point: 5.1509

>T170255 WP_188063773.1 NZ_CP060388:367652-367975 [Sphingobium sp. KCTC 72723]
MKFLVDAQLPPALCRWLHEQGHEAVHVCDIGMIAASDVEIAARAEVDGAALVSKDEDFVVLRLPDRFALLWLRCGNATNR
ALVGWLEARWARIVVLLEGGERLVEVR

Download         Length: 324 bp

>T170255 NZ_CP077237:2305180-2306499 [Aeromonas sp. FDAARGOS 1404]
ATGGCCAATCTAGCTGTCTACATGAACGGCTATCGGGTAGGCACATTCACCAAAACTACCAGCGGTGCCCATCAGTTTCA
GTACCATGAGTCATGGCTAGCACAACCGGGCAGCCGTCCGATCTCACTCTCCATGCCATTGCGCCATCAGGCCTACCGGG
GCGATGAAGCCTATAACTTCTTCGACAACCTGCTGCCAGATAATACGGAGGTGAGGAACAGGGTTGTAGCACGCTATCAA
GCGGCATCAACTCAGCCCTTCGATCTGCTCAGTTGCATTGGCCAGGATAGCGTAGGGGCATTACAGCTGGTTACCGAAGG
ACACGATGTTCCAGATGTCAGGCGAATCGACTACAAGGCCCTTTCCGATGACGAGCTCAAGCAGATCCTGACCAGCTACA
AATCAGGAATCCCTTTGGGGATGGTCAGGGAACAAGAGGAGTTTCGGATCTCTATCGCCGGGGCGCAAGAAAAGACTGCG
CTGCTCTATCTCGATGGCCTTTGGTACTTGCCACTCAACGTAACGCCGACAACCCACATTATCAAACTCCCTATCGGCAA
GATTGAAAGCCACTCCTACTCGATAGACCTCTCCCAGAGCGTAGAAAACGAATATCTCTGCACTCTGATTGCCAAGGAGT
TTGGTCTACCCGTACCTCACTGCTTCATGATGCAGGTTGGCCAGGTCAAAGCACTGGCTGTTGAACGCTTCGACAGACGT
TACGCTGCCGATCGCAGTTGGATAATGCGCCTTCCCCAAGAAGATTTCTGTCAGGTATTGAATGTTCCGTCAGCACGGAA
ATACGAGAGCCATGGAGGACCAGGGATCACTGACATCATGGAAACCTTGCTGGGCTCTGCGACACCAGAACAGGATCGCT
ACCTGTTCATGAAATCTCAGGTCCTGTTCTGGCTGCTGGCAGCCACCGATGGCCATGCAAAGAACTTCTCGGTCTTTATT
GAACCGGAAGGGCGTTTTCGCCTGACCCCTTTTTACGACATCCTATCTGTCTATCCAGTGTTTGGCGGCCGAGGCCTCAA
CCGAAGGGACGCCAAGCTCGCTATGGGCCTAGCAAGCAGCAAGGGAAAGAAGTACTCCATTGAGCAGATATTCCCGCGTC
ATTTCTTCCAAACGGCAAAAACTGTGGGATTTGAGCGTTCTGCTATGGAAGAGATCCTGACAGAACTGGCCAACTCCGTT
GATGATGTTATTGAGCGCGTTACCCAGCAATTGCCAGCAGACTTCCCCGATACCATCAGCAGCACCATTCTAGAGGGCCT
AAAAGCCCGCTCAGCCAGGCTGATAAAGGGTTGGGATTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 7853.08 Da        Isoelectric Point: 4.1755

>AT170255 WP_188063772.1 NZ_CP060388:367422-367655 [Sphingobium sp. KCTC 72723]
MTLAGFPRIAVDPAVCGGRPIVVGTRVRVSDILEMLAGGAGVDEIVADFPYLSADDVRAALGYAAAMADHPVVLAAE

Download         Length: 234 bp

>AT170255 NZ_CP077237:2304926-2305180 [Aeromonas sp. FDAARGOS 1404]
ATGAAAGTAACCAGCGCCAAGCAGCTGAGCGCCTGTATCAAGGATGCCAGGCTTTCTCAAAAGCTCTCTCAAGGCAAAGT
GGCCGAGAAAGTGGGGATTAGGCAAGACACAGTCTCCAGCTTCGAGCTCAATCCTGAGTCCACCAAGCTGGAAACCCTGT
TCAAGATCCTCGCAGCACTCGAATTGTCAGTGGATATCAAACCCCGCAATGAGTCATCCGAGAGTCCGGCATCGGGCTGG
AAGGAGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References