Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 367422..367975 Replicon chromosome
Accession NZ_CP060388
Organism Sphingobium sp. KCTC 72723

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SPBM01_RS01980 Protein ID WP_188063773.1
Coordinates 367652..367975 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SPBM01_RS01975 Protein ID WP_188063772.1
Coordinates 367422..367655 (+) Length 78 a.a.

Genomic Context

SPBM01_RS01940SPBM01_RS01945SPBM01_RS01975SPBM01_RS01980SPBM01_RS01985SPBM01_RS01950SPBM01_RS01955SPBM01_RS01960SPBM01_RS01965SPBM01_RS01970SPBM01_RS01990SPBM01_RS01995
Location: 363301..364050 (750 bp)
Type: Others
Protein ID: WP_188062383.1
Location: 364047..364976 (930 bp)
Type: Others
Protein ID: WP_188063766.1
Location: 367422..367655 (234 bp)
Type: Antitoxin
Protein ID: WP_188063772.1
Location: 367652..367975 (324 bp)
Type: Toxin
Protein ID: WP_188063773.1
Location: 368056..368928 (873 bp)
Type: Others
Protein ID: WP_188063774.1
Location: 365044..365247 (204 bp)
Type: Others
Protein ID: WP_188063767.1
Location: 365351..365551 (201 bp)
Type: Others
Protein ID: WP_188063768.1
Location: 365631..365846 (216 bp)
Type: Others
Protein ID: WP_188063769.1
Location: 366039..367091 (1053 bp)
Type: Others
Protein ID: WP_188063770.1
Location: 367175..367375 (201 bp)
Type: Others
Protein ID: WP_188063771.1
Location: 368934..371852 (2919 bp)
Type: Others
Protein ID: WP_188063775.1
Location: 371982..372131 (150 bp)
Type: Others
Protein ID: WP_188063776.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SPBM01_RS01940363301..364050+750WP_188062383.1electron transfer flavoprotein subunit beta/FixA family protein-
SPBM01_RS01945364047..364976+930WP_188063766.1FAD-binding protein-
SPBM01_RS01950365044..365247-204WP_188063767.1hypothetical protein-
SPBM01_RS01955365351..365551-201WP_188063768.1hypothetical protein-
SPBM01_RS01960365631..365846-216WP_188063769.1cold-shock protein-
SPBM01_RS01965366039..367091-1053WP_188063770.1hypothetical protein-
SPBM01_RS01970367175..367375-201WP_188063771.1addiction module antitoxin-
SPBM01_RS01975367422..367655+234WP_188063772.1DUF433 domain-containing proteinAntitoxin
SPBM01_RS01980367652..367975+324WP_188063773.1DUF5615 family PIN-like proteinToxin
SPBM01_RS01985368056..368928+873WP_188063774.1FRG domain-containing protein-
SPBM01_RS01990368934..371852-2919WP_188063775.1excinuclease ABC subunit UvrA-
SPBM01_RS01995371982..372131-150WP_188063776.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--314140..40804593905


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-74)

Antitoxin

Protein of unknown function DUF433

(9-64)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11928.88 Da        Isoelectric Point: 5.1509

>T170255 WP_188063773.1 NZ_CP060388:367652-367975 [Sphingobium sp. KCTC 72723]
MKFLVDAQLPPALCRWLHEQGHEAVHVCDIGMIAASDVEIAARAEVDGAALVSKDEDFVVLRLPDRFALLWLRCGNATNR
ALVGWLEARWARIVVLLEGGERLVEVR

Download         Length: 324 bp

>T170255 NZ_CP077237:2305180-2306499 [Aeromonas sp. FDAARGOS 1404]
ATGGCCAATCTAGCTGTCTACATGAACGGCTATCGGGTAGGCACATTCACCAAAACTACCAGCGGTGCCCATCAGTTTCA
GTACCATGAGTCATGGCTAGCACAACCGGGCAGCCGTCCGATCTCACTCTCCATGCCATTGCGCCATCAGGCCTACCGGG
GCGATGAAGCCTATAACTTCTTCGACAACCTGCTGCCAGATAATACGGAGGTGAGGAACAGGGTTGTAGCACGCTATCAA
GCGGCATCAACTCAGCCCTTCGATCTGCTCAGTTGCATTGGCCAGGATAGCGTAGGGGCATTACAGCTGGTTACCGAAGG
ACACGATGTTCCAGATGTCAGGCGAATCGACTACAAGGCCCTTTCCGATGACGAGCTCAAGCAGATCCTGACCAGCTACA
AATCAGGAATCCCTTTGGGGATGGTCAGGGAACAAGAGGAGTTTCGGATCTCTATCGCCGGGGCGCAAGAAAAGACTGCG
CTGCTCTATCTCGATGGCCTTTGGTACTTGCCACTCAACGTAACGCCGACAACCCACATTATCAAACTCCCTATCGGCAA
GATTGAAAGCCACTCCTACTCGATAGACCTCTCCCAGAGCGTAGAAAACGAATATCTCTGCACTCTGATTGCCAAGGAGT
TTGGTCTACCCGTACCTCACTGCTTCATGATGCAGGTTGGCCAGGTCAAAGCACTGGCTGTTGAACGCTTCGACAGACGT
TACGCTGCCGATCGCAGTTGGATAATGCGCCTTCCCCAAGAAGATTTCTGTCAGGTATTGAATGTTCCGTCAGCACGGAA
ATACGAGAGCCATGGAGGACCAGGGATCACTGACATCATGGAAACCTTGCTGGGCTCTGCGACACCAGAACAGGATCGCT
ACCTGTTCATGAAATCTCAGGTCCTGTTCTGGCTGCTGGCAGCCACCGATGGCCATGCAAAGAACTTCTCGGTCTTTATT
GAACCGGAAGGGCGTTTTCGCCTGACCCCTTTTTACGACATCCTATCTGTCTATCCAGTGTTTGGCGGCCGAGGCCTCAA
CCGAAGGGACGCCAAGCTCGCTATGGGCCTAGCAAGCAGCAAGGGAAAGAAGTACTCCATTGAGCAGATATTCCCGCGTC
ATTTCTTCCAAACGGCAAAAACTGTGGGATTTGAGCGTTCTGCTATGGAAGAGATCCTGACAGAACTGGCCAACTCCGTT
GATGATGTTATTGAGCGCGTTACCCAGCAATTGCCAGCAGACTTCCCCGATACCATCAGCAGCACCATTCTAGAGGGCCT
AAAAGCCCGCTCAGCCAGGCTGATAAAGGGTTGGGATTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 7853.08 Da        Isoelectric Point: 4.1755

>AT170255 WP_188063772.1 NZ_CP060388:367422-367655 [Sphingobium sp. KCTC 72723]
MTLAGFPRIAVDPAVCGGRPIVVGTRVRVSDILEMLAGGAGVDEIVADFPYLSADDVRAALGYAAAMADHPVVLAAE

Download         Length: 234 bp

>AT170255 NZ_CP077237:2304926-2305180 [Aeromonas sp. FDAARGOS 1404]
ATGAAAGTAACCAGCGCCAAGCAGCTGAGCGCCTGTATCAAGGATGCCAGGCTTTCTCAAAAGCTCTCTCAAGGCAAAGT
GGCCGAGAAAGTGGGGATTAGGCAAGACACAGTCTCCAGCTTCGAGCTCAATCCTGAGTCCACCAAGCTGGAAACCCTGT
TCAAGATCCTCGCAGCACTCGAATTGTCAGTGGATATCAAACCCCGCAATGAGTCATCCGAGAGTCCGGCATCGGGCTGG
AAGGAGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References