Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-YefM
Location 2251266..2251768 Replicon chromosome
Accession NZ_CP060296
Organism Variovorax sp. PAMC28562

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag H7F36_RS10680 Protein ID WP_187054645.1
Coordinates 2251505..2251768 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H7F36_RS10675 Protein ID WP_187054905.1
Coordinates 2251266..2251508 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7F36_RS10650 2246498..2247352 - 855 WP_187054641.1 ABC transporter permease -
H7F36_RS10655 2247349..2248149 - 801 WP_187054642.1 ATP-binding cassette domain-containing protein -
H7F36_RS10660 2248146..2249018 - 873 WP_187054643.1 putative selenate ABC transporter substrate-binding protein -
H7F36_RS10665 2249066..2250118 + 1053 WP_187054904.1 selenide, water dikinase SelD -
H7F36_RS10670 2250317..2251138 - 822 WP_187054644.1 hypothetical protein -
H7F36_RS10675 2251266..2251508 + 243 WP_187054905.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H7F36_RS10680 2251505..2251768 + 264 WP_187054645.1 Txe/YoeB family addiction module toxin Toxin
H7F36_RS10685 2251765..2252157 + 393 WP_187054646.1 hypothetical protein -
H7F36_RS10690 2252187..2254061 - 1875 WP_187054647.1 DUF3857 domain-containing protein -
H7F36_RS10695 2254358..2256550 - 2193 WP_187054648.1 xanthine dehydrogenase family protein molybdopterin-binding subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(25-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10172.95 Da        Isoelectric Point: 10.0963

>T170250 WP_187054645.1 NZ_CP060296:2251505-2251768 [Variovorax sp. PAMC28562]
VRWEVVYAKHAIKDAKKLAAAGLKGKALELLEVLVVDPFQNPPPYEKLVGDLDGAYSRRINIQHRLVYEVFKKERIVRVL
RMWSHYE

Download         Length: 264 bp

>T170250 NZ_CP077236:c2115010-2114723 [Lelliottia amnigena]
ATGACTGAACTCACTCATTACGATCCTGCCCGGGCGCTTATCAATGATGATGAAATTAGCGTATTCATGGCTGATGCGCT
AGAAACTGGCGATTCTGCCTACATTGCTAAAGCATTAGGGATCGTTGCCCGCGCAAAAGGAATGTCTACCATTGCGACAC
AAACGGGTTTGTCTCGCGAACAGCTGTATCGCTCTTTTAGTGAAAAAGGTAACCCAACGCTTAAAACCACGCTTGCCGTT
ATGAAAGCGCTGGGTCTTGGATTGACGATTAAAAGTGCTGAAGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8830.19 Da        Isoelectric Point: 8.0064

>AT170250 WP_187054905.1 NZ_CP060296:2251266-2251508 [Variovorax sp. PAMC28562]
ITPITASEARASLYRLIDQTSESHQPILISGKRSSAVLVSADDWQAIQETLYLLSVPGMRESIKKGMAEPLDKSAKKLCW

Download         Length: 243 bp

>AT170250 NZ_CP077236:c2115320-2115003 [Lelliottia amnigena]
ATGAAGGAGATTGTTCAAACAGAATCCTTCCGTTGCTGGGAGCAAAACGTAAACGATCCACGTGCAAAAACGCTTATTGC
AGCGCGTTTATTCCGCCTGGCTAATGGTCTGCCGGGGGATGTAAAACCTGTTGGAGAAGGTATCAGCGAGCTACGGATTC
ATTACGGCCCGGGTTACAGGATCTATTTTAAATCGCAGGGAAACGTACTGATCATTTTGCTCAGTGGCGGCAATAAAAAT
AGTCAGGATAAAGACATCATTCTGGCAAAGACACTCGCAAGATCACTCGAACATCGGGAGTTTATACACCATGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References