Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 2711558..2712193 Replicon chromosome
Accession NZ_CP060293
Organism Paenibacillus sp. PAMC21692

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag H7F31_RS10675 Protein ID WP_087569551.1
Coordinates 2711843..2712193 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag H7F31_RS10670 Protein ID WP_087569552.1
Coordinates 2711558..2711839 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7F31_RS10650 2706642..2707472 - 831 WP_187104143.1 phytanoyl-CoA dioxygenase family protein -
H7F31_RS10655 2707624..2708496 + 873 WP_187104144.1 AraC family transcriptional regulator -
H7F31_RS10660 2708695..2709882 + 1188 WP_108996040.1 outer membrane lipoprotein carrier protein LolA -
H7F31_RS10665 2710049..2711239 + 1191 WP_187104145.1 alanine racemase -
H7F31_RS10670 2711558..2711839 + 282 WP_087569552.1 CopG family ribbon-helix-helix protein Antitoxin
H7F31_RS10675 2711843..2712193 + 351 WP_087569551.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
H7F31_RS10680 2712358..2713143 + 786 WP_187104146.1 SAF domain-containing protein -
H7F31_RS10685 2713140..2713991 + 852 WP_187104147.1 hypothetical protein -
H7F31_RS10690 2713988..2715376 + 1389 WP_187104148.1 CpaF/VirB11 family protein -
H7F31_RS10695 2715434..2716369 + 936 WP_187104149.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-45)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12795.76 Da        Isoelectric Point: 5.1171

>T170245 WP_087569551.1 NZ_CP060293:2711843-2712193 [Paenibacillus sp. PAMC21692]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEMDAATHGFDRDSVVLLEQI
RTIDKQRLTDKITHLDDETMRKVDDALLISVGLIDF

Download         Length: 351 bp

>T170245 NZ_CP077233:21750-21917 [Acinetobacter pittii]
TTGCGCTTAAAATCTCAAGAAGGTATTGCTCGTGTTATGTATTGCACACTAGTCGGTAAACGCATTGTAATGCTCCATAG
TTTTGTTAAGAAAACCCAAAAAACACCTAAGCAAGATCTAAACCTAGCACTTGACCGCATGAAAGAGGTGAAAAATGCGA
ACACATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10748.35 Da        Isoelectric Point: 7.2046

>AT170245 WP_087569552.1 NZ_CP060293:2711558-2711839 [Paenibacillus sp. PAMC21692]
VANIHNTKRIMISLPDQLLEEVDGIVAKENSNRSEFIRQAMKLYLVERKKRQIRESMQRGYMEMARINLNMASEAFQAEE
EADHTLGRLVSGV

Download         Length: 282 bp

>AT170245 NZ_CP077233:21904-22191 [Acinetobacter pittii]
ATGCGAACACATGAAGAAATGAAAGCACTTGCATTATCTCGTTCAGCAGTGCGTACCGAATACGAACGAATTGAACGTGA
AGAAATGCCCTTGCTCGATATGGTACTTACTGCACTTCGAGAGGCAGGTCTATCCCAAGCGCAAATCGCGGAACGCATGG
GAACAAATGTACCTGCCGTTTCACGGCTAGAAAAAGCATTGATCACAGGCAAACCATCACCATCTATTGCCACATTGCAA
AAATACGCTGCGGCAATTGGTAAACATGTTGAAGTGCGTTTTGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References