Detailed information of TA system TA170243

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4237030..4237546
• Replicon: chromosome
• Accession: NZ_CP060289
• Organism: Pseudomonas protegens strain H1F10A

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GGD92_RS19065
• Protein ID: WP_103740982.1
• Coordinates: 4237030..4237311 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GGD92_RS19070
• Protein ID: WP_103740990.1
• Coordinates: 4237301..4237546 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GGD92_RS19045	4233282..4234172	-	891	WP_179598832.1	HlyD family secretion protein	-
GGD92_RS19050	4234169..4234378	-	210	WP_011058538.1	DUF1656 domain-containing protein	-
GGD92_RS19055	4234375..4236462	-	2088	WP_179598834.1	FUSC family protein	-
GGD92_RS19060	4236459..4236887	-	429	WP_016967883.1	winged helix DNA-binding protein	-
GGD92_RS19065	4237030..4237311	-	282	WP_103740982.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GGD92_RS19070	4237301..4237546	-	246	WP_103740990.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
GGD92_RS19075	4237611..4237856	-	246	WP_016967889.1	DUF2789 domain-containing protein	-
GGD92_RS19080	4237871..4238332	-	462	WP_016967891.1	YbaK/EbsC family protein	-
GGD92_RS19085	4238441..4240051	-	1611	WP_179598836.1	glycosyltransferase family 39 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10812.70 Da
• Isoelectric Point: 10.2298

>T170243 WP_103740982.1 NZ_CP060289:c4237311-4237030 [Pseudomonas protegens]
MTYSLEFLPSAHKEWSKLGHTLREQFKKKLAERLEVPRIPADALHGLPDCYKIKLKASGYRLVYQVIEERVVVCVVAVGK
RERGTVYEQARKR

Nucleotide

• Length: 282 bp

>T170243 NZ_CP077233:c10694-10392 [Acinetobacter pittii]
ATGTACTCAATATATACCACAGAAGCCTTTGATGATTGGTTTACCAAGTTAAAAGATCAACAGGCAAAAAGACGCATACA
AGTCCGAATTGATCGGGTTGAAGATGGGAACTTTGGAGATACTGAACCAGTCGGTGAAGGTGTTTCTGAGTTACGTTTCT
TCTTTGGACCTGGCTATAGGATTTATTACTGCAAGCAAGGGCAAAGGGTCGTTATTCTCTTAGCAGGTGGAGATAAGTCT
ACGCAAAGTAAAGATATAAAACTTGCCCTACAATTAGCACAAGATTTAGAGGAGGAGTTGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8741.07 Da
• Isoelectric Point: 4.5164

>AT170243 WP_103740990.1 NZ_CP060289:c4237546-4237301 [Pseudomonas protegens]
MQSILADKAVSVSELKKNPSAVLSAAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIVRARSHETPVPVSLDD
L

Nucleotide

• Length: 246 bp

>AT170243 NZ_CP077233:c10391-10110 [Acinetobacter pittii]
ATGGCTATCAAACTTCGTAAATGGGATAGTGCTGAGCATCTTAAAACAGAAGAAGATATGCAAGCTTACCTACAAGCCTG
TATCGATGAATCTAATGGTGATGCTGCATTCATTGCTAAAGCTTTAGGTAACATTGCTAAAGCTAAAGGAATGGCTCAAT
TATCACGAGATACAGGTCTAGGCCGAGAAAGTCTTTACAAAGCACTTTCTGGTGATGTTAACCCTAGTTTTGATACTGTG
ATTAAAGTTGTAAAAGCACTGAATTTACGCTTAGCAATTTAA