170241

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 3693112..3693708 Replicon chromosome
Accession NZ_CP060289
Organism Pseudomonas protegens strain H1F10A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GGD92_RS16645 Protein ID WP_016968234.1
Coordinates 3693112..3693414 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GGD92_RS16650 Protein ID WP_179598414.1
Coordinates 3693418..3693708 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GGD92_RS16625 3688353..3689666 - 1314 WP_179598412.1 precorrin-3B synthase -
GGD92_RS16630 3689798..3691012 + 1215 WP_016968231.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
GGD92_RS16635 3691106..3692203 + 1098 WP_047301443.1 cobalt-precorrin-5B (C(1))-methyltransferase -
GGD92_RS16640 3692200..3692928 + 729 WP_016968233.1 cobalt-precorrin-6A reductase -
GGD92_RS16645 3693112..3693414 + 303 WP_016968234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GGD92_RS16650 3693418..3693708 + 291 WP_179598414.1 putative addiction module antidote protein Antitoxin
GGD92_RS16655 3693808..3694206 + 399 WP_179598416.1 DUF2946 domain-containing protein -
GGD92_RS16660 3694271..3694750 + 480 WP_173655926.1 copper chaperone PCu(A)C -
GGD92_RS16665 3694806..3695216 + 411 WP_179598417.1 DUF2946 domain-containing protein -
GGD92_RS16670 3695305..3697437 + 2133 WP_179598419.1 TonB-dependent copper receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-91)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11605.34 Da        Isoelectric Point: 10.7824

>T170241 WP_016968234.1 NZ_CP060289:3693112-3693414 [Pseudomonas protegens]
MFIFEQTQAFTHWLLRLKDPQGKTRVLARIRAAQLGRFGDCEPVGDGVYEMRIHRGPGYRVYFSRRGNRIYLLLIGGDKS
TQKRDIQQARQLAHDLKSEG

Download         Length: 303 bp

>T170241 NZ_CP077232:3645504-3645893 [Acinetobacter pittii]
TTGATAAAAGAATTAAATTTTGAGCTGAAATATAGCCGTGTCTCGGTAATATTTCAGCTTTTTGTTGGTTTGGGTTTAGC
AATCTTGCTTTATCAATTATTAATGCCGATATGGTGGCTATGTGCTGTCATTTTTATATTTATTGGTTTTATTTTCTTTT
TAAAGCAAACACAAATATCTCAAATTGAATATTTAGATCAAAAATTATGGTCGGTTGCATATTACTCGGAGAAAGCGGTT
CATCTTGTTGAAATTAGAAAAATAATTGATTATCAGATGTTTGTAGTGATTTATTTTGAAGGGACATCTGCGAAAGTAGC
AACTGTTTGGTTCGATCAGCTTTCTATTGAGCAGTGGAAAAGATTAAAAGTTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10386.92 Da        Isoelectric Point: 5.8268

>AT170241 WP_179598414.1 NZ_CP060289:3693418-3693708 [Pseudomonas protegens]
MHTPVTRFDAAEYLKTPEDMVAYLDACFEEDAGDGKLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLNVSPA

Download         Length: 291 bp

>AT170241 NZ_CP077232:3645240-3645497 [Acinetobacter pittii]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCGTATGTAAAAAACTATTATTTAAAAGCTGATCCGGCAGAAAAAGCATTATTTGCAGAGTTAGTTGATCAAGAAG
ATCCAGATTTATTAGATTGGTTCATGGAAGTTTCTGAGCCTCCACGTACTGAGTTACGTGAATTTATTTATAAATTAAAA
CAGTATGTACATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References