Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 3026865..3027754 Replicon chromosome
Accession NZ_CP060288
Organism Pseudomonas mendocina strain CPS5

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag H7683_RS14105 Protein ID WP_209449199.1
Coordinates 3027356..3027754 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag H7683_RS14100 Protein ID WP_244973821.1
Coordinates 3026865..3027356 (+) Length 164 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7683_RS14050 (H7683_14045) 3021912..3022238 - 327 WP_209449193.1 DUF2523 domain-containing protein -
H7683_RS24465 3022238..3023722 - 1485 WP_244973820.1 virulence factor TspB C-terminal domain-related protein -
H7683_RS14060 (H7683_14055) 3023870..3024076 - 207 WP_041979008.1 major capsid protein -
H7683_RS14065 (H7683_14060) 3024082..3024300 - 219 WP_209449194.1 hypothetical protein -
H7683_RS14070 (H7683_14065) 3024311..3024490 - 180 WP_209449195.1 hypothetical protein -
H7683_RS14075 (H7683_14070) 3024506..3024889 - 384 WP_209449196.1 hypothetical protein -
H7683_RS14080 (H7683_14075) 3025139..3025450 - 312 WP_209449197.1 hypothetical protein -
H7683_RS14085 (H7683_14080) 3025461..3025664 - 204 WP_244973906.1 DUF5447 family protein -
H7683_RS14090 (H7683_14085) 3025938..3026156 - 219 WP_003245701.1 hypothetical protein -
H7683_RS14095 (H7683_14090) 3026300..3026566 + 267 WP_061237382.1 hypothetical protein -
H7683_RS14100 (H7683_14095) 3026865..3027356 + 492 WP_244973821.1 Panacea domain-containing protein Antitoxin
H7683_RS14105 (H7683_14100) 3027356..3027754 + 399 WP_209449199.1 hypothetical protein Toxin
H7683_RS14110 (H7683_14105) 3027832..3028101 - 270 WP_209449200.1 hypothetical protein -
H7683_RS14115 (H7683_14110) 3028881..3029330 - 450 WP_013713973.1 DMT family transporter -
H7683_RS14120 (H7683_14115) 3029519..3030307 - 789 WP_041976722.1 aldolase/citrate lyase family protein -
H7683_RS14125 (H7683_14120) 3030318..3031121 - 804 WP_041976724.1 carbon-nitrogen hydrolase family protein -
H7683_RS14130 (H7683_14125) 3031206..3032204 - 999 WP_013713976.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3018270..3028101 9831


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(6-116)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14909.19 Da        Isoelectric Point: 8.5230

>T170236 WP_209449199.1 NZ_CP060288:3027356-3027754 [Pseudomonas mendocina]
MTGTIFRKGTLLILSGPVEHLHIVMNDPVYSHEHGWDGVLAVNISSIKPGIYHDPSCIVQPGQHPFVSRDSWVVYREAAV
MRCDRLEYKLASGEIRGHQTTTEELFANVRAGFDISKMVPQKIKRFIRAHSI

Download         Length: 399 bp

>T170236 NZ_CP077212:126983-127270 [Enterobacter cloacae]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 164 a.a.        Molecular weight: 18716.17 Da        Isoelectric Point: 4.5890

>AT170236 WP_244973821.1 NZ_CP060288:3026865-3027356 [Pseudomonas mendocina]
MSYLKLMKLLYLADRESMDRYSVPMSDDAAVSMPHGPVLSTTLNLMTGQIESPFWRSWISPDANHEVSLSRPVNSLEDLD
ELSEADFEILELVWQKFGHLRRWEIRDLTHRDCPEWVDPGRSSAPIDPRAVFTALGRSEEQANAETKEIFERRVLGRAVS
ELI

Download         Length: 492 bp

>AT170236 NZ_CP077212:126744-126983 [Enterobacter cloacae]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References