Detailed information of TA system TA170231

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 437956..438597
• Replicon: chromosome
• Accession: NZ_CP060285
• Organism: Acinetobacter baumannii strain XYAB2018

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: H7X63_RS02140
• Protein ID: WP_000607077.1
• Coordinates: 438208..438597 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: H7X63_RS02135
• Protein ID: WP_011860336.1
• Coordinates: 437956..438201 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H7X63_RS02115	433460..434467	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
H7X63_RS02120	434486..434863	+	378	WP_001216380.1	50S ribosomal protein L17	-
H7X63_RS02125	435045..436535	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
H7X63_RS02130	436584..437756	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
H7X63_RS02135	437956..438201	+	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
H7X63_RS02140	438208..438597	+	390	WP_000607077.1	membrane protein	Toxin
H7X63_RS02145	439367..440452	+	1086	WP_000049106.1	hypothetical protein	-
H7X63_RS02150	440530..441096	+	567	WP_000651538.1	rhombosortase	-
H7X63_RS02155	441284..443479	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T170231 WP_000607077.1 NZ_CP060285:438208-438597 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T170231 NZ_CP077211:3278363-3278466 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT170231 WP_011860336.1 NZ_CP060285:437956-438201 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT170231 NZ_CP077211:c3278471-3278328 [Enterobacter cloacae]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT