Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2133214..2133359 Replicon chromosome
Accession NZ_CP060281
Organism Klebsiella pneumoniae strain ent1077

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2133250..2133352 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2133214..2133359 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7U30_RS10135 2128344..2130404 + 2061 WP_004151449.1 oligopeptidase B -
H7U30_RS10140 2130408..2131067 - 660 WP_002911407.1 exodeoxyribonuclease X -
H7U30_RS10145 2131146..2131376 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H7U30_RS10150 2131489..2131863 + 375 WP_004151448.1 CopC domain-containing protein YobA -
H7U30_RS10155 2131867..2132736 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
H7U30_RS10160 2132753..2133091 + 339 WP_002911404.1 YebY family protein -
- 2133214..2133359 - 146 - - Antitoxin
- 2133250..2133352 + 103 - - Toxin
H7U30_RS10165 2133727..2133870 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
H7U30_RS10170 2133975..2134943 - 969 WP_004151446.1 VirK/YbjX family protein -
H7U30_RS10175 2135100..2135753 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
H7U30_RS10180 2135750..2135941 - 192 WP_002911395.1 YebW family protein -
H7U30_RS10185 2136039..2136278 - 240 WP_002911393.1 YebV family protein -
H7U30_RS10190 2136394..2137827 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T170214 NZ_CP060281:2133250-2133352 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT170214 NZ_CP060281:c2133359-2133214 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References