Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE(toxin)
Location 4751557..4752122 Replicon chromosome
Accession NZ_CP060276
Organism Serratia ureilytica strain CC119

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag D0895_RS22465 Protein ID WP_182265722.1
Coordinates 4751844..4752122 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag D0895_RS22460 Protein ID WP_182074225.1
Coordinates 4751557..4751826 (+) Length 90 a.a.

Genomic Context

D0895_RS22460D0895_RS22465D0895_RS22485D0895_RS22445D0895_RS22450D0895_RS22455D0895_RS22470D0895_RS22475D0895_RS22480
Location: 4751557..4751826 (270 bp)
Type: Antitoxin
Protein ID: WP_182074225.1
Location: 4751844..4752122 (279 bp)
Type: Toxin
Protein ID: WP_182265722.1
Location: 4755612..4755950 (339 bp)
Type: Others
Protein ID: WP_025304525.1
Location: 4747818..4749035 (1218 bp)
Type: Others
Protein ID: WP_187048451.1
Location: 4749167..4749742 (576 bp)
Type: Others
Protein ID: WP_033645386.1
Location: 4749815..4751338 (1524 bp)
Type: Others
Protein ID: WP_033645261.1
Location: 4752123..4752848 (726 bp)
Type: Others
Protein ID: WP_046688553.1
Location: 4752848..4754533 (1686 bp)
Type: Others
Protein ID: WP_033651731.1
Location: 4754689..4755258 (570 bp)
Type: Others
Protein ID: WP_033636286.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D0895_RS224454747818..4749035-1218WP_187048451.1aspartate aminotransferase family protein-
D0895_RS224504749167..4749742-576WP_033645386.1aminodeoxychorismate synthase component II-
D0895_RS224554749815..4751338-1524WP_033645261.1DUF853 family protein-
D0895_RS224604751557..4751826+270WP_182074225.1hypothetical proteinAntitoxin
D0895_RS224654751844..4752122+279WP_182265722.1type II toxin-antitoxin system RelE/ParE family toxinToxin
D0895_RS224704752123..4752848-726WP_046688553.1two-component system response regulator BtsR-
D0895_RS224754752848..4754533-1686WP_033651731.1sensor histidine kinase-
D0895_RS224804754689..4755258-570WP_033636286.1peptidylprolyl isomerase A-
D0895_RS224854755612..4755950+339WP_025304525.1PTS lactose/cellobiose transporter subunit IIA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10289.01 Da        Isoelectric Point: 10.0357

>T170191 WP_182265722.1 NZ_CP060276:4751844-4752122 [Serratia ureilytica]
VKLIWTEPAIADRLAIYEWLELKNPAAAAENDVKIADAAARLVHHPASGKTGRIAGTRELVISPSYLLVYEWAAQRVIIL
AIVHTRRRWPPV

Download         Length: 279 bp

>T170191 NZ_CP077098:c2239379-2239017 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAGTTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10311.56 Da        Isoelectric Point: 5.2791

>AT170191 WP_182074225.1 NZ_CP060276:4751557-4751826 [Serratia ureilytica]
MPESTVVIRVDEELKTAFASAAKAADRTASQLLRDFMREFVSRQAQQEEYDQWLREKVEVSRKALREGKLADDEEVAAYF
AERRAKSTR

Download         Length: 270 bp

>AT170191 NZ_CP077098:c2239546-2239376 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References