Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE(toxin)
Location 4751557..4752122 Replicon chromosome
Accession NZ_CP060276
Organism Serratia ureilytica strain CC119

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag D0895_RS22465 Protein ID WP_182265722.1
Coordinates 4751844..4752122 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag D0895_RS22460 Protein ID WP_182074225.1
Coordinates 4751557..4751826 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0895_RS22445 4747818..4749035 - 1218 WP_187048451.1 aspartate aminotransferase family protein -
D0895_RS22450 4749167..4749742 - 576 WP_033645386.1 aminodeoxychorismate synthase component II -
D0895_RS22455 4749815..4751338 - 1524 WP_033645261.1 DUF853 family protein -
D0895_RS22460 4751557..4751826 + 270 WP_182074225.1 hypothetical protein Antitoxin
D0895_RS22465 4751844..4752122 + 279 WP_182265722.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D0895_RS22470 4752123..4752848 - 726 WP_046688553.1 two-component system response regulator BtsR -
D0895_RS22475 4752848..4754533 - 1686 WP_033651731.1 sensor histidine kinase -
D0895_RS22480 4754689..4755258 - 570 WP_033636286.1 peptidylprolyl isomerase A -
D0895_RS22485 4755612..4755950 + 339 WP_025304525.1 PTS lactose/cellobiose transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10289.01 Da        Isoelectric Point: 10.0357

>T170191 WP_182265722.1 NZ_CP060276:4751844-4752122 [Serratia ureilytica]
VKLIWTEPAIADRLAIYEWLELKNPAAAAENDVKIADAAARLVHHPASGKTGRIAGTRELVISPSYLLVYEWAAQRVIIL
AIVHTRRRWPPV

Download         Length: 279 bp

>T170191 NZ_CP077098:c2239379-2239017 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAGTTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10311.56 Da        Isoelectric Point: 5.2791

>AT170191 WP_182074225.1 NZ_CP060276:4751557-4751826 [Serratia ureilytica]
MPESTVVIRVDEELKTAFASAAKAADRTASQLLRDFMREFVSRQAQQEEYDQWLREKVEVSRKALREGKLADDEEVAAYF
AERRAKSTR

Download         Length: 270 bp

>AT170191 NZ_CP077098:c2239546-2239376 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References