Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1712486..1713011 Replicon chromosome
Accession NZ_CP060276
Organism Serratia ureilytica strain CC119

Toxin (Protein)


Gene name relE Uniprot ID A0A8B4GJ35
Locus tag D0895_RS08195 Protein ID WP_033633469.1
Coordinates 1712486..1712770 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8B4GIN1
Locus tag D0895_RS08200 Protein ID WP_004928423.1
Coordinates 1712760..1713011 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0895_RS08170 1707690..1708823 + 1134 WP_149542527.1 putrescine ABC transporter ATP-binding subunit PotG -
D0895_RS08175 1708848..1709810 + 963 WP_042784087.1 putrescine ABC transporter permease PotH -
D0895_RS08180 1709807..1710652 + 846 WP_042784088.1 putrescine ABC transporter permease PotI -
D0895_RS08185 1710814..1711293 + 480 WP_047024958.1 YbjO family protein -
D0895_RS08190 1711362..1712489 + 1128 WP_187048768.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
D0895_RS08195 1712486..1712770 - 285 WP_033633469.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D0895_RS08200 1712760..1713011 - 252 WP_004928423.1 prevent-host-death protein Antitoxin
D0895_RS08205 1713113..1713847 - 735 WP_015377297.1 arginine ABC transporter substrate-binding protein -
D0895_RS08210 1714047..1714715 - 669 WP_072627969.1 arginine ABC transporter permease ArtM -
D0895_RS08215 1714715..1715431 - 717 WP_072627968.1 arginine ABC transporter permease ArtQ -
D0895_RS08220 1715441..1716172 - 732 WP_004928409.1 arginine ABC transporter substrate-binding protein -
D0895_RS08225 1716205..1716933 - 729 WP_089192582.1 arginine ABC transporter ATP-binding protein ArtP -
D0895_RS08230 1717198..1717740 - 543 WP_033642535.1 lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10789.91 Da        Isoelectric Point: 10.6941

>T170177 WP_033633469.1 NZ_CP060276:c1712770-1712486 [Serratia ureilytica]
MTYKLEFEEHALKEFKKLSPVIREQFKKKLASVLVNPHVPANKLAGLPDCYKIKLRASGFRLVYRVMETEIVVLVLSVGK
RERSAAYTAAKKRL

Download         Length: 285 bp

>T170177 NZ_CP077095:4260865-4261143 [Pseudomonas xantholysinigenes]
ATGATTCGAAGCTTCCGCTGCGCCGAGACGCAAACCTTGTTCACCACCGGCAAGACCCGCCGCTGGTCGCAGATCAAGTC
CATCGCCGAGCGCAAGCTGGCCATGCTCGATGCCGCCAAGGCTCTGCGTGACCTGCGCTCGCCTCCCGGCAACCGCCTCG
AACAGTTGTCCGGCGATCGCAGCGGGCAACACAGCATCCGAATCAACGATCAGTGCCGCATCTGCTTCAACTGGAGCGAC
GAAGGCCCGGCAAACGTTGAAATCATCGACTACCACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9108.39 Da        Isoelectric Point: 4.5203

>AT170177 WP_004928423.1 NZ_CP060276:c1713011-1712760 [Serratia ureilytica]
MTVQPILADSAVSISDFKKSPNAALKEAQGQPVAVLTNGKISGYYVSPETWEAIAEYLEDIELAEIVRSRMNGKRIKVNL
DDL

Download         Length: 252 bp

>AT170177 NZ_CP077095:4261152-4261451 [Pseudomonas xantholysinigenes]
ATGCTCACTAACGGTATGCGTCCCATCCATCCCGGCGAAGTCCTGCGTGAGGACTTCCAGAAGGAACTGGGCCTGAGCGC
CGCCGCCCTGGCACGCGCGCTCGGTGTCGCTACTCCAACCGTCAACAACATCCTGCGCGAACGCGGTGGCGTGTCCGCCG
ACATGGCGTTGCGCCTGTCGATCTGCCTGGACACCACGCCGGAGTTCTGGCTCAACCTGCAGTCAGCGTTCGATCTGCGC
ACCGCCCAACAACAGCATGGCGATGAAATCATCGGCTCAGTCCAGCGCCTGGTCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A8B4GJ35

Antitoxin

Source ID Structure
AlphaFold DB A0A8B4GIN1

References