Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1579623..1580171 Replicon chromosome
Accession NZ_CP060276
Organism Serratia ureilytica strain CC119

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag D0895_RS07610 Protein ID WP_028127948.1
Coordinates 1579869..1580171 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag D0895_RS07605 Protein ID WP_025302143.1
Coordinates 1579623..1579859 (+) Length 79 a.a.

Genomic Context

D0895_RS07590D0895_RS07595D0895_RS07600D0895_RS07605D0895_RS07610D0895_RS07630D0895_RS07615D0895_RS07620D0895_RS07625
Location: 1576110..1577645 (1536 bp)
Type: Others
Protein ID: WP_042784031.1
Location: 1577698..1578618 (921 bp)
Type: Others
Protein ID: WP_089191398.1
Location: 1578628..1579536 (909 bp)
Type: Others
Protein ID: WP_187048755.1
Location: 1579623..1579859 (237 bp)
Type: Antitoxin
Protein ID: WP_025302143.1
Location: 1579869..1580171 (303 bp)
Type: Toxin
Protein ID: WP_028127948.1
Location: 1583245..1584402 (1158 bp)
Type: Others
Protein ID: WP_033650593.1
Location: 1580207..1581049 (843 bp)
Type: Others
Protein ID: WP_187048756.1
Location: 1581064..1582188 (1125 bp)
Type: Others
Protein ID: WP_016928454.1
Location: 1582219..1583139 (921 bp)
Type: Others
Protein ID: WP_164107264.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D0895_RS075901576110..1577645+1536WP_042784031.1glutathione ABC transporter substrate-binding protein GsiB-
D0895_RS075951577698..1578618+921WP_089191398.1glutathione ABC transporter permease GsiC-
D0895_RS076001578628..1579536+909WP_187048755.1glutathione ABC transporter permease GsiD-
D0895_RS076051579623..1579859+237WP_025302143.1type II toxin-antitoxin system CcdA family antitoxinAntitoxin
D0895_RS076101579869..1580171+303WP_028127948.1CcdB family proteinToxin
D0895_RS076151580207..1581049-843WP_187048756.1S-formylglutathione hydrolase-
D0895_RS076201581064..1582188-1125WP_016928454.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase-
D0895_RS076251582219..1583139-921WP_164107264.1LysR family transcriptional regulator-
D0895_RS076301583245..1584402+1158WP_033650593.1YbfB/YjiJ family MFS transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-99)

Antitoxin

Post-segregation antitoxin CcdA

(8-78)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11210.98 Da        Isoelectric Point: 5.0196

>T170176 WP_028127948.1 NZ_CP060276:1579869-1580171 [Serratia ureilytica]
ITVYDNTYPASAYPYLLDVQSDLIDVLSTRLMIPLYALDNVRVKISARLCPEIEVNGEKFLVMTHEMAAVRISQIGKAVG
NVNEHRNQIKAAIDFLIDGF

Download         Length: 303 bp

>T170176 NZ_CP077095:3200453-3201037 [Pseudomonas xantholysinigenes]
ATGGATCTCGACCTGCTCGCCAGTCGCCTGGCGTTTCTACGCGAGGCCGAACGCCTCAAGGATGTGCTACGCAGTGCCCA
TACCTCATCTGGGCGCACGGAAAGCACAGCAGAGCATAGCTGGCGATTGTCCCTGATGGCGCTGGTGTTCGCCGACCAGA
TGCCAGGTCTTGACCTGCTGAAAGTCATCCAGCTGTGCGTGGTGCACGACCTGGGCGAGGCGTTGCATGGCGATATCCCC
GCCGTCGACCAGGTGCCGGGCCAGCACAAGGACCAGCAGGAGTTCGAAGACCTGCAACAGCTCTGCGCCAGCCTCGACGC
CCCCTTGCGCGCGCAAATCCTGCAACTGTGGCAGGAATATGCCGCGGCCCACAGCGCCGAAGCCAAGACGGTCAAGGCCC
TGGACAAGCTCGAGACCCTGCTGCAGCACACCCAGGGCGCCAACCCCGGCGACTTCGACTATGCCTTCAACCTCGACTAC
GGGCGTCGCTATACTGACGCCGCGCCGCTGTTTCGCGCCTTGCGCGAACAGATCGACAACGACACGCGCCAGCGTATGAC
ACACATTGCCCAGAAGACACCATGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8967.04 Da        Isoelectric Point: 5.0807

>AT170176 WP_025302143.1 NZ_CP060276:1579623-1579859 [Serratia ureilytica]
MANSNVTKKTVNVTIDRDLFQRAKSLGVNVSSVLTDALSVRVRDIEIQQWREQNRAALEELNRITEENGLLSDEYRTF

Download         Length: 237 bp

>AT170176 NZ_CP077095:3199808-3200371 [Pseudomonas xantholysinigenes]
ATGCCCACCACTGCCCTGCCCCAGGCCGCCGAGCTGGGTGTCGCGCTACGCCGCTGGCGCCTGTTGCATCGGGTCAAGCA
AGCGCATGCCGCCCAACTGTTCAGCGTGGCGCAGTCGACCATCTCGCGCTGGGAAAACGGCCTGCAGGCCATGAATCCTG
ATGAGCAGGCACGGCTCGGGCAGTTGCTCGGCGCACGCCTGAGCGCGGCGGCCGATCAGGCCCTGGCGCGCCTGGTCGAA
GGCAGCCAGCAGCCGGTGCACCTGGTCTGCGACCTCAGCCATCGCCTGCTGGCCTGTTCGCCCGCCCGCGCCGCCGAGTT
CAGCCTGCCGCTGTCGGCGCTCATGGGCCGCTCGCTGTGGCGGTTCAGCAGCGAGGCGATCATCCAGCGCGAAGCAAGCC
TGCAAGCCTTGGGTTGGCGCGAGCAACTGGCGCCACCGGCGCTGGCGTTCGATACCGGCTGCAATCGCTCGCGGGTGGTC
CCCATCAGCGCCGGGACCTGCCGCTGGACGCGGCTGATCCTCGCCGATGGCAGCGCGGCGCGCCTGGTCGAGACCCTGGC
GTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References