Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 92591..93126 Replicon chromosome
Accession NZ_CP060276
Organism Serratia ureilytica strain CC119

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D0895_RS00445 Protein ID WP_164057663.1
Coordinates 92851..93126 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D0895_RS00440 Protein ID WP_047025978.1
Coordinates 92591..92851 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0895_RS00420 87910..88560 + 651 WP_033645112.1 DcrB-related protein -
D0895_RS00425 88601..89206 + 606 WP_033645111.1 glutathione S-transferase -
D0895_RS00430 89276..90670 + 1395 WP_042783408.1 L-seryl-tRNA(Sec) selenium transferase -
D0895_RS00435 90667..92508 + 1842 WP_187048493.1 selenocysteine-specific translation elongation factor -
D0895_RS00440 92591..92851 + 261 WP_047025978.1 ribbon-helix-helix domain-containing protein Antitoxin
D0895_RS00445 92851..93126 + 276 WP_164057663.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D0895_RS00450 93307..94554 - 1248 WP_033633516.1 MFS transporter -
D0895_RS00455 94772..95764 + 993 WP_187048494.1 acyltransferase -
D0895_RS00460 95759..96682 - 924 WP_187048495.1 DJ-1/PfpI family protein -
D0895_RS00465 96685..97236 - 552 WP_072626481.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10616.41 Da        Isoelectric Point: 10.3377

>T170174 WP_164057663.1 NZ_CP060276:92851-93126 [Serratia ureilytica]
MELKWTSKVLPDLARLFEFLALANRTAAANSVKALVAAPKALLDNPRLGERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp

>T170174 NZ_CP077095:311809-312000 [Pseudomonas xantholysinigenes]
ATGAACAGCCGTGAAATGATTTCGGTGATCGAGGCGGATGGTTGGTACCTGGTGCGTTGCAAAGGCAGCCACCATCACTT
CAAGCACCCTGACAAACCTGGGCTGGTAACCATCCCGCACCCGAAGAAGGACCTGCTGCCCGCCACCGCGGCCAGCATCC
TGCGCCAGGCGCGGATCGTCTACGCCAGCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9667.98 Da        Isoelectric Point: 4.5201

>AT170174 WP_047025978.1 NZ_CP060276:92591-92851 [Serratia ureilytica]
MNTKVITAHVPLPLAEKVDEMAAKLDRSRGWIVKQALAAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp

>AT170174 NZ_CP077095:312018-312431 [Pseudomonas xantholysinigenes]
ATGTTGTTTCCCATCGCCATCCTTCCCGGTGACGACCAGTACGCCTGGGGCGTTGAAGTGCCGGACATCCCTGGCTGCTT
TTCGGCGGGTGAAGACCTCGACAACGCCATCGCCATGGCCCGCGAGGCGATCGAGGGCCATCTCGAGCTGCTCGCCCAGG
ACCAGCAGGAAATTCCCAAGGCCAGCAAGGTCGCCGTGCATGCGGCCAATCCGGCCTATGCCGGCTGCACCTGGGCGTTG
ATCGATATCGATATCACCCGCTACCTGGGCAAGGCCGAAAAGCTCAACATCACCCTGCCGGCCTACCTGCTCACCCGTAT
CGACAGCTATGTGCAGAACCACCCCGAACACAAGAGCCGCTCGGGCTTCCTGGCCGAGGCGGCGCTGAAGATCCTCCAGG
GCGAGGGTAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References