Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) toxT-higA/Tad-HTH_37
Location 4405710..4406304 Replicon chromosome
Accession NZ_CP060263
Organism Dickeya zeae strain JZL7

Toxin (Protein)


Gene name toxT Uniprot ID -
Locus tag H7F34_RS19735 Protein ID WP_219952004.1
Coordinates 4405984..4406304 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag H7F34_RS19730 Protein ID WP_219952003.1
Coordinates 4405710..4405994 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7F34_RS19710 4401543..4402415 + 873 WP_016942974.1 L-ribulose-5-phosphate 3-epimerase -
H7F34_RS19715 4402513..4403286 + 774 WP_016942973.1 HTH-type transcriptional regulator UlaR -
H7F34_RS19720 4403456..4404679 - 1224 WP_019845172.1 aspartate aminotransferase family protein -
H7F34_RS19725 4404813..4405388 - 576 WP_023640890.1 aminodeoxychorismate synthase component II -
H7F34_RS19730 4405710..4405994 - 285 WP_219952003.1 helix-turn-helix transcriptional regulator Antitoxin
H7F34_RS19735 4405984..4406304 - 321 WP_219952004.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H7F34_RS19740 4406445..4406666 - 222 Protein_3873 helicase RepA family protein -
H7F34_RS19745 4406602..4406850 + 249 WP_219953504.1 type II toxin-antitoxin system RelE/ParE family toxin -
H7F34_RS19750 4406834..4407157 + 324 WP_219952005.1 DNA-binding transcriptional regulator -
H7F34_RS19755 4407368..4409422 - 2055 WP_219952006.1 hypothetical protein -
H7F34_RS22230 4409561..4409722 - 162 Protein_3877 integrase -
H7F34_RS19760 4409939..4411144 - 1206 WP_219952007.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(38-89)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12162.17 Da        Isoelectric Point: 9.6070

>T170155 WP_219952004.1 NZ_CP060263:c4406304-4405984 [Dickeya zeae]
MYELIFHPEAASEIYDLEPVMQAKALKGLEKLEAKGPELRYPDTDIIDGGLFELRVGRKDISRTFFAYAKGRKIYILRTF
IKKTPKTPKAEIALAKSRWEELKDGS

Download         Length: 321 bp

>T170155 NZ_CP077092:c895161-894871 [Pseudomonas iranensis]
ATGACCGAAGAATTCGCCCGTTTTGACGCCGCCGAGTACCTCAAAACTCCCGAGGACATGGCGGCATATCTAGATGCCTG
TTTTGACGATGACGAAGGCGACGGCGTCCTTATCCGTGCAGCGCTCAATGACATCGCCCGGGCTCAAGGCATGACACAAG
TGGCGCGGGATGCAGGTTTGGGCCGCGAAAGTCTTTATAAAGCCCTGAGTAGCACTGGCAATCCCGAATTCGCAACTATC
ATGAAAGTCATGAAGGCTCTGGGTTTGAGATTGCATGCCGTAACGCTGTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10126.72 Da        Isoelectric Point: 10.0102

>AT170155 WP_219952003.1 NZ_CP060263:c4405994-4405710 [Dickeya zeae]
MAVKGINFSEVKAKALSHPEVKKAYEDETQEEALRAVLIEMKSKSGLTSTEIAARMGVSQPAVSRLERNVSSASISTLQR
YAAACGMRLKLSLG

Download         Length: 285 bp

>AT170155 NZ_CP077092:c895467-895165 [Pseudomonas iranensis]
ATGATCGCTTTTGAACGATCCCGCATATTTTCCGAATGGCTCGACTCCTTGAAAGACATCAAAGGGAAAGGCCGAATCAT
CTCCAGAATTAAAACAGCCGAAAATGGCAACTTCGGCGATTGCGGGTTCGTCGGTGACACTGTTTATGAAATGCGTGTTC
ATTACGGCCCTGGTTACAGGATGTACTTCACACGCAAAGGCGAAGTGATTTATCTGCTGCTGATCGGGGGCGATAAATCG
ACACAAAAAAGAGATATCAAACGCGCCGTGCAGATGGCTCATAGCATCGGAAATGAGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References