Detailed information of TA system TA170154

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 3348560..3349904
• Replicon: chromosome
• Accession: NZ_CP060263
• Organism: Dickeya zeae strain JZL7

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: H7F34_RS14980
• Protein ID: WP_168361985.1
• Coordinates: 3348948..3349904 (+)
• Length: 319 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: -
• Locus tag: H7F34_RS14975
• Protein ID: WP_033576632.1
• Coordinates: 3348560..3348955 (+)
• Length: 132 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H7F34_RS14950	3344143..3346593	-	2451	WP_168361987.1	DUF3772 domain-containing protein	-
H7F34_RS22215	3347173..3347298	-	126	Protein_2946	phage baseplate protein	-
H7F34_RS14960	3347291..3347710	-	420	WP_219951591.1	phage GP46 family protein	-
H7F34_RS14965	3347719..3347994	-	276	Protein_2948	baseplate protein	-
H7F34_RS14970	3348019..3348313	+	295	Protein_2949	PIN domain-containing protein	-
H7F34_RS14975	3348560..3348955	+	396	WP_033576632.1	DUF6088 family protein	Antitoxin
H7F34_RS14980	3348948..3349904	+	957	WP_168361985.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
H7F34_RS14985	3350491..3351705	+	1215	Protein_2952	tyrosine-type recombinase/integrase	-
H7F34_RS14990	3352092..3352520	-	429	WP_219951592.1	hypothetical protein	-
H7F34_RS14995	3352615..3353783	+	1169	WP_219951593.1	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3347155..3361459	14304

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (34-302)

Antitoxin

• Protein of unknown function DUF6088 (7-114)

Sequences

Toxin

Protein

• Length: 319 a.a.
• Molecular weight: 36723.20 Da
• Isoelectric Point: 5.3283

>T170154 WP_168361985.1 NZ_CP060263:3348948-3349904 [Dickeya zeae]
MDELTALFPDVADALGIESVSIVEKDYYIVELLRLLRHLTFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPTANFLQ
QSSRSQRKNIRKDIIRTITESIVASRVFSFDDDYPKVTRDEYRYNEIPVRYPQMYSQIPCLRPFIKLELMETDLLESSET
RDICSLVTDVTKKGEMVRAFPCATIVSTQAEKLISIMRRTAASMRDLERVEDKSLVRHIYDNFCIVREKGVNVAALTHFI
QECIEQDIARYGNQYPEFCESPVEELKKGLEELASNPVYKMRYQQFLAPMVFGEIRVSWEEAYSCFRQTVLSVLKSYR

Nucleotide

• Length: 957 bp

>T170154 NZ_CP077092:693212-693574 [Pseudomonas iranensis]
ATGGTGCGCCGACAGCCCCCTCAGCGGGGTGACGTTTACTGGATTGATCCAAACCCAGTGGCGGGGCGGGAGATGATGAA
CAGACATCGCTTTGTGGTGATCACGCCCAGAGAGATCAACGCATTGGGCGTGAGCATGACGGTGCCTGTTACTAGCGGTG
GGAATTTCAGCCGGAATATGGGTTTGGCGGTCGCCATTACTGGCCACGAAACCAATGGTGTAGCGGTGTGTAATCAGGTT
CGCAGTTTTGACATAGAACAACGGGTACGAGACGGCACGGCCAAATTCATCGAGCGACTGGATGACGTGACAATGTCTGA
CATCGTCGACCGTGTAATCAGTGCAATCGACCCGCTAAGCTGA

Antitoxin

Protein

• Length: 132 a.a.
• Molecular weight: 14443.79 Da
• Isoelectric Point: 11.0325

>AT170154 WP_033576632.1 NZ_CP060263:3348560-3348955 [Dickeya zeae]
MTIKARIQSRLKRSKRYVFTRDDFKDLAGYDQVGRALRELVKEGQLLKVGYGVYTKARKNVITGRLMPASPGGSAAVVIE
ALERLKVDYRLADAASAYNSGKSTQVPASIEIKTPPRFKRVLSVGNSKLNG

Nucleotide

• Length: 396 bp

>AT170154 NZ_CP077092:692943-693212 [Pseudomonas iranensis]
ATGTCCGTAACTTCCAAGATACGCCGCCAAGGCGGCGCTGCCGTCATTACGATTCCGCCCACGCTTTTAAAGTTGTTGCA
TCTGGAGGTTGGCGCACAGCTAGAGCTGAATGTGGTCGATGGCGAACTGATTGCTCGTCCAGCCGTAGCCGCTACGCGTA
AGCGTTATAGTTTGTCAGAGCTACTCGAAGGCGCAGAAGAATTGCAGAAACTTAACGCCCAGACTAGCGAGACCCTTGAA
GGTGATTCTGTCGGCCGGGAGCTGGGTTGA