Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1620624..1621374 Replicon chromosome
Accession NZ_CP060263
Organism Dickeya zeae strain JZL7

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag H7F34_RS07060 Protein ID WP_168362935.1
Coordinates 1620624..1620881 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag H7F34_RS07065 Protein ID WP_168362934.1
Coordinates 1620889..1621374 (+) Length 162 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7F34_RS07050 1617332..1619482 - 2151 WP_219952937.1 formate dehydrogenase subunit alpha -
H7F34_RS07055 1619517..1620059 - 543 WP_016943624.1 4Fe-4S dicluster domain-containing protein -
H7F34_RS07060 1620624..1620881 + 258 WP_168362935.1 DUF4160 domain-containing protein Toxin
H7F34_RS07065 1620889..1621374 + 486 WP_168362934.1 addiction module antitoxin Antitoxin
H7F34_RS07070 1621459..1621968 - 510 WP_219952938.1 hydrogenase maturation peptidase HycI -
H7F34_RS07075 1621961..1622359 - 399 WP_016943629.1 formate hydrogenlyase maturation HycH family protein -
H7F34_RS07080 1622359..1623147 - 789 WP_012885279.1 NADH-quinone oxidoreductase subunit B family protein -
H7F34_RS07085 1623144..1623713 - 570 WP_016943631.1 hydrogenase 4 subunit H -
H7F34_RS07090 1623724..1625451 - 1728 WP_168362930.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-73)

Antitoxin

Uncharacterized protein HI1420

(80-156)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9865.48 Da        Isoelectric Point: 7.5161

>T170141 WP_168362935.1 NZ_CP060263:1620624-1620881 [Dickeya zeae]
MPEIDRLAGLIFYLYFYDDERHHLPHVHVCYGNHELIISIRTGTEIEGYLPNTKRKLAIAHIMAHREQLLSMWAQAVIGK
NPGKL

Download         Length: 258 bp

>T170141 NZ_CP077090:4342216-4342500 [Pseudomonas zeae]
ATGCAGATTAAGTGGCGACCCAAGGCTCGGGTCGAACTCTCGAAAATCCTGAAGTACATTGGCGAGCGAAATTTTGTAGC
GGCGACTGCACTTCACAAGTCCGTCGTAAAAACTACATCTGCGCTTTGTTGGCATCCACACCTGTATCGCAAAGGCCGCT
CTCCCGGCACTCGAGAGATTGTGGTAAGCCCGAACTATCTCGTCGTTTATCAAGTGGCGGACCAAATTGAGATTGTGAGC
ATCTTGCATGCGCGTCAGGAGTACCCTCGATGCGACCCCGGTTAA

Antitoxin


Download         Length: 162 a.a.        Molecular weight: 17779.04 Da        Isoelectric Point: 6.8503

>AT170141 WP_168362934.1 NZ_CP060263:1620889-1621374 [Dickeya zeae]
MHKIVDVDVTGDFSLRLTYDDGLISDVNLYHYASHSVFSHASQFIRFGLLPDGSLEWPDITLSSSALREKGTYVGHTLAV
RERNFADIISRAFYDAVIENRPEILQAALKTAVDKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLEE
K

Download         Length: 486 bp

>AT170141 NZ_CP077090:4342020-4342226 [Pseudomonas zeae]
ATGATCGACCCAAAGATGATTGACCCACTGTGCCCAGTCGTCTCGGACCTTGATCCTGAAGAACAGGCTGCGAGTTATGA
CCGTTGGTTCAGGGCGGAAGTACAAGCGTCTCTCGATGATCCGCGCCCGAGTATTCCCCATGAGCAAGTGATGGAGGAGA
TCAATGCCTTGATGGAATCAATGCGCAAAAGCGCTGATGCAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References