Detailed information of TA system TA170139

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 714455..715133
• Replicon: chromosome
• Accession: NZ_CP060263
• Organism: Dickeya zeae strain JZL7

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: H7F34_RS03305
• Protein ID: WP_219952591.1
• Coordinates: 714702..715133 (+)
• Length: 144 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: H7F34_RS03300
• Protein ID: WP_038906203.1
• Coordinates: 714455..714721 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H7F34_RS03285	711617..712225	-	609	WP_019846260.1	HD domain-containing protein	-
H7F34_RS03290	712438..713088	+	651	WP_019846261.1	hemolysin III family protein	-
H7F34_RS03295	713166..714146	-	981	WP_219952590.1	tRNA-modifying protein YgfZ	-
H7F34_RS03300	714455..714721	+	267	WP_038906203.1	FAD assembly factor SdhE	Antitoxin
H7F34_RS03305	714702..715133	+	432	WP_219952591.1	protein YgfX	Toxin
H7F34_RS03310	715222..715740	-	519	WP_168363479.1	flavodoxin FldB	-
H7F34_RS03315	715918..717243	-	1326	WP_168363478.1	MFS transporter	-
H7F34_RS03320	717507..718406	+	900	WP_168363477.1	site-specific tyrosine recombinase XerD	-
H7F34_RS03325	718494..719210	+	717	WP_012883376.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (7-79)

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 16917.56 Da
• Isoelectric Point: 11.5023

>T170139 WP_219952591.1 NZ_CP060263:714702-715133 [Dickeya zeae]
VAQWQCDLRVSWRMQLFSLLTHGFLMLMILLAPWPDGYAPLWLGLVTLVVFDFVRSQRSIKSRQGEISLRGDNQLHWQQR
DWQIVRRPWFMRNGVLLSLRAVDGKGQQRLWLASDSMGSEEWRLLRQQLQQPTLHGTESSRHH

Nucleotide

• Length: 432 bp

>T170139 NZ_CP077090:2137231-2137443 [Pseudomonas zeae]
GTGCAAAGCAGGTTATTGATCAAGGAGCTGGAGGAGGCGGGTTGGACGCTGGACCGGATTACCGGCAGTCATCACATTTT
CAGGCACCGTTACAACCCTTACACGATTCCCGTTCCTCATCCGAAAAAGGATTTGCCGTTGGGGACAGTCAAAAGCATCA
GGAGACGTGCCGGGTTGTACAACCCGCCAGCCAGTTTCGAAGGAGATCCATAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10446.96 Da
• Isoelectric Point: 5.5981

>AT170139 WP_038906203.1 NZ_CP060263:714455-714721 [Dickeya zeae]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQQFIRLLQCDDPDLFNWLMNHGEPVDPGLKRMVSLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT170139 NZ_CP077090:2137443-2137847 [Pseudomonas zeae]
ATGCAATATCCAATCTGTATCGAGTGGGGAGACGAGAATACTGCCATCGGTATTCAGATCCCCGATATTCCCGGCGCCGT
TACAGCAGGGGATAGCTTTGAAGATGCCTACAACGCGGCAGTTGAAGTCGCCCACATCCTGCTGCAGGAGATTGCGGCGG
ACGGGGAGTCGATTCCTATGCCGACTTCGGCATCCGCTCATCGCAGTAATCCGGACTTTGCCGACATGGGGTGGGGCATG
CTCGAGCTGGACATTTCGCCCTATCTCGGCAAGACCGAGAAGGTCAACGTAACGCTGCCCGGTTATGTGATTCAGCGCAT
CGATCGTTATGTGCGCGAACACAATGTCAAAAGCCGCTCCTCCTTTCTGGCGGACGCGGCGATGGAGAAACTGGTTCGTT
ATTAA