Detailed information of TA system TA170133

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 2246403..2246934
• Replicon: chromosome
• Accession: NZ_CP060244
• Organism: Entomobacter blattae strain G55GP

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JGUZn3_RS10040
• Protein ID: WP_203413376.1
• Coordinates: 2246653..2246934 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: JGUZn3_RS10035
• Protein ID: WP_203413375.1
• Coordinates: 2246403..2246666 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JGUZn3_RS10010	2242374..2242688	-	315	WP_203413370.1	hypothetical protein	-
JGUZn3_RS10015	2242690..2243331	-	642	WP_203413371.1	hypothetical protein	-
JGUZn3_RS10020	2243407..2243661	+	255	WP_203413372.1	type II toxin-antitoxin system HicA family toxin	-
JGUZn3_RS10025	2243658..2243996	+	339	WP_203413373.1	type II toxin-antitoxin system HicB family antitoxin	-
JGUZn3_RS10030	2243993..2246278	-	2286	WP_203413374.1	hypothetical protein	-
JGUZn3_RS10035	2246403..2246666	+	264	WP_203413375.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
JGUZn3_RS10040	2246653..2246934	+	282	WP_203413376.1	type II toxin-antitoxin system YafQ family toxin	Toxin
JGUZn3_RS10045	2247052..2247894	+	843	WP_203413377.1	YqaJ viral recombinase family protein	-
JGUZn3_RS10050	2247891..2248871	+	981	WP_203413378.1	recombinase RecT	-
JGUZn3_RS10055	2249094..2249495	+	402	WP_203413379.1	hypothetical protein	-
JGUZn3_RS10060	2249560..2249850	+	291	WP_203413380.1	hypothetical protein	-
JGUZn3_RS10065	2249847..2250713	+	867	WP_203413381.1	DNA cytosine methyltransferase	-
JGUZn3_RS10070	2250707..2250922	+	216	WP_203413382.1	hypothetical protein	-
JGUZn3_RS10075	2250926..2251501	+	576	WP_203413383.1	dUTP diphosphatase	-
JGUZn3_RS10080	2251476..2251805	+	330	WP_203413384.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2230845..2258273	27428

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-92)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-83)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10873.44 Da
• Isoelectric Point: 8.0279

>T170133 WP_203413376.1 NZ_CP060244:2246653-2246934 [Entomobacter blattae]
MRTIEYSTRFKKDYKRESKGQYRKTLDADLEAVLSLLLSDTPLPTKYKDHILIGNWGNYRECHIKPDLLLIYQLPDENTL
SLARLGSHSELFS

Nucleotide

• Length: 282 bp

>T170133 NZ_CP077089:710680-710985 [Pseudomonas tensinigenes]
ATGACTGAGATTCTTCGAAGTTCTACATTTTCCAACTGGCTTTTAAAGTTGGCTGATAGTCGCGCCAGGATGCGTATTCA
GGTGCGAATTGATCGTATGGCTGACGGAAATTTTGGCGATGTCAAAGCCATCGGTGAAGGGCTCAGCGAAGTCAGAATTG
ACTATGGCCCCGGATATCGAGTCTATTTCATGCAACAAGGTCGGCAAGTGGTCATCCTCCTTTGCGGCGGAGACAAGAGC
AGCCAACCCCGAGACATCAAGCAAGCCAGGCTCATCGCGGAGTCCTGGCAGGAGCAAAACCCATGA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9652.26 Da
• Isoelectric Point: 10.1428

>AT170133 WP_203413375.1 NZ_CP060244:2246403-2246666 [Entomobacter blattae]
MKTDSIIRTRINAETKEKAMHALKEMGITASDAIRLLMTRIAEEKKLPFEVKVPNAATQQAMNELNAGKGKKVSSLSKLM
ADLHEND

Nucleotide

• Length: 264 bp

>AT170133 NZ_CP077089:710982-711269 [Pseudomonas tensinigenes]
ATGACCGAAAAATTCACTCGTTGGGACTCAGCCGAGTACCTCAAGACAGAAGAGGACATGGCTAACTATCTGGACGCCTG
CATGGAGGAGGCTGGAGATGACCCGGCTTTTATCGCCAAGGCACTTGGCACCATAGCGAGAGCGCGAGGCATGACTCAGG
TCGCACGTGACGCAGGGTTGTCCCGAGAGAGCCTCTACCGCGCACTATCAGGTGAAGGAAACCCCGAGTTCGGAACAATC
CTGAAAGTGGTGAAGGCGTTAGGGTTGAAGTTACACGCCAGTACTTGA