Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 1411818..1412527 Replicon chromosome
Accession NZ_CP060244
Organism Entomobacter blattae strain G55GP

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag JGUZn3_RS06235 Protein ID WP_203412728.1
Coordinates 1412039..1412527 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag JGUZn3_RS06230 Protein ID WP_203414840.1
Coordinates 1411818..1412051 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGUZn3_RS06205 1407137..1408216 - 1080 WP_203412723.1 Flp pilus assembly complex ATPase component TadA -
JGUZn3_RS06210 1408213..1409409 - 1197 WP_203412724.1 type IV secretion system protein VirB10 -
JGUZn3_RS06215 1409410..1410381 - 972 WP_203412725.1 TrbG/VirB9 family P-type conjugative transfer protein -
JGUZn3_RS06220 1410384..1411079 - 696 WP_203412726.1 type IV secretion system protein -
JGUZn3_RS06225 1411063..1411608 - 546 WP_203412727.1 hypothetical protein -
JGUZn3_RS06230 1411818..1412051 + 234 WP_203414840.1 DUF1778 domain-containing protein Antitoxin
JGUZn3_RS06235 1412039..1412527 + 489 WP_203412728.1 GNAT family N-acetyltransferase Toxin
JGUZn3_RS06240 1413065..1413304 + 240 WP_203412729.1 type II toxin-antitoxin system CcdA family antitoxin -
JGUZn3_RS06245 1413304..1413606 + 303 WP_203412730.1 CcdB family protein -
JGUZn3_RS06250 1413676..1414704 - 1029 WP_203412731.1 type IV secretion system protein -
JGUZn3_RS06255 1414701..1415033 - 333 WP_203412732.1 EexN family lipoprotein -
JGUZn3_RS06260 1415036..1415803 - 768 WP_203412733.1 hypothetical protein -
JGUZn3_RS06265 1415800..1415961 - 162 WP_203412734.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1358594..1422616 64022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-148)

Antitoxin

Vibrio phage ICP1, Orf50

(3-75)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17719.41 Da        Isoelectric Point: 10.1688

>T170130 WP_203412728.1 NZ_CP060244:1412039-1412527 [Entomobacter blattae]
VGGMRPVPLSPHHDLEDFNSGDLSLDEWLRRKALKNQVTGALRTFVYLESNRVKGYYALASGALDQAGAPGSIRRNMPDP
IPVAVLARLAVDSSLQGQGLGASLLKDVVLRLTEAAEIVGIRGILVHAVSDRAKSFYKKYGFIDTIGDPYRLVFSLKQKR
QT

Download         Length: 489 bp

>T170130 NZ_CP077087:c2572013-2571729 [Pseudomonas monsensis]
ATGCAGATTAAGTGGCGACCCAAGGCTCGGGTCGAACTCTCGAAAATCCTGAAGTACATTGGCGAGCGAAATTTTTTAGC
GGCGACTGCACTTCACAAGTCCGTCGTAAAAACTACATCTGCGCTTTGTTGGCATCCACACCTGTATCGCAAAGGCCGCT
CTCCCGGCACTCGAGAGATTGTGGTAAGCCCGAACTATCTCGTCGTTTATCAAGTGGCGGACCAAATTGAGATTGTGAGC
ATCTTGCATACGCGTCAGGAGTACCCTCGACGCGACCCCGGTTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8863.88 Da        Isoelectric Point: 4.3813

>AT170130 WP_203414840.1 NZ_CP060244:1411818-1412051 [Entomobacter blattae]
MLEETRQLIDAAAQITGKTRTEFITESSRRSAEDTLLEQTYIRVSPESYAHFLSVLDEPPSGEGYERLMKVKTPWEE

Download         Length: 234 bp

>AT170130 NZ_CP077087:c2572209-2572003 [Pseudomonas monsensis]
ATGATCGACCCGTCCTTGATCGACCCACTGTGCCCGGTTGTTTCGGATCTTGATCCCGAGGAACAGGCTGCGAGTTATGA
CCGTTGGTTTCGGGCCGAAGTACAGGCCTCTCTCGATGATCCGCGCCCGAGTATTCCCCATGAGCAAGTGATGGAGGAAA
TCAACGCCTTGATGGAATCAATGCGCAAAAGCGCTGATGCAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References