170129

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 328693..329174 Replicon chromosome
Accession NZ_CP060244
Organism Entomobacter blattae strain G55GP

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag JGUZn3_RS01440 Protein ID WP_203414739.1
Coordinates 328920..329174 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag JGUZn3_RS01435 Protein ID WP_203412742.1
Coordinates 328693..328914 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGUZn3_RS01410 324628..325719 + 1092 WP_203414008.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
JGUZn3_RS01415 325732..326361 + 630 WP_203414009.1 riboflavin synthase -
JGUZn3_RS01420 326343..327623 + 1281 WP_203414010.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
JGUZn3_RS01425 327716..328198 + 483 WP_203414011.1 6,7-dimethyl-8-ribityllumazine synthase -
JGUZn3_RS01435 328693..328914 + 222 WP_203412742.1 ribbon-helix-helix protein, CopG family Antitoxin
JGUZn3_RS01440 328920..329174 + 255 WP_203414739.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JGUZn3_RS01445 329248..330318 - 1071 WP_203412741.1 hypothetical protein -
JGUZn3_RS01450 330469..330795 - 327 WP_203412740.1 hypothetical protein -
JGUZn3_RS01455 330909..331742 + 834 WP_203412739.1 lytic transglycosylase domain-containing protein -
JGUZn3_RS01460 331735..332064 + 330 WP_203412738.1 hypothetical protein -
JGUZn3_RS01465 332048..332380 + 333 WP_203412737.1 TrbC/VirB2 family protein -
JGUZn3_RS01470 332392..332739 + 348 WP_203412736.1 VirB3 family type IV secretion system protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 328380..367541 39161


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9897.64 Da        Isoelectric Point: 10.3997

>T170129 WP_203414739.1 NZ_CP060244:328920-329174 [Entomobacter blattae]
IMWEIRFSETASKEFSKLDKPVAKRLMNFLEERVVTLEDPRNLGKALRGHLGELWSYRVGDFRIIADIQDKKLCILILKT
GHRR

Download         Length: 255 bp

>T170129 NZ_CP077087:c942616-942314 [Pseudomonas monsensis]
ATGATCGAACTTGAACGATCCCGTGTATTTTCCGAATGGCTCGACTCGTTGAAAGACATCATCGGCAAAGGCCGAATCAT
CTCCAGACTTCGAGCAGCCGAACATGGCAACTTTGGCGATTACGGTTTTGTCGGTGACACCGTTTACGAAATGCGTGTTC
ACTACGGTCCTGGTTACAGGATGTACTTCACTCGTCGAGACGAAGTGATTTATCTGCTTTTGATCGGGGGCGATAAATCG
ACACAACGGCGTGATATCAAGCGCGCCGTACAAATGGCACATAGCATCGGTAATGAGGAGTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8454.64 Da        Isoelectric Point: 5.1088

>AT170129 WP_203412742.1 NZ_CP060244:328693-328914 [Entomobacter blattae]
MTTTVRLNQNIEERLDFLAKQTGRTKTYYIAQLIENGLDELEDYYLAADVLEKIRKGKEKTISSSDLKKTLDL

Download         Length: 222 bp

>AT170129 NZ_CP077087:c942310-942020 [Pseudomonas monsensis]
ATGACCGAAAAATTCACCCGTTTCGACGCCGCCGAATACCTCAAAACTCCCGAGGATATGGCGGCGTATCTGGACGCTTG
CTTTGATGATGATGAAGGCGATGGCGTACTCATCCGTGCAGCACTGAATGACATAGCCCGAGCTCAGGGCATGACACAGG
TGGCACGTGATGCCGGCCTGGGTCGTGAAAGTCTCTATAAAGCGCTGAGCAGCACTGGTAACCCCGAATTCGCAACTATC
ATGAAGGTCATGAAGGCTTTGGGTTTGAGATTGCACGCCGTCGCGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References