Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2515794..2516390 Replicon chromosome
Accession NZ_CP060201
Organism Pseudomonas protegens strain H1F5C

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GGI48_RS11720 Protein ID WP_016968234.1
Coordinates 2515794..2516096 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GGI48_RS11725 Protein ID WP_179598414.1
Coordinates 2516100..2516390 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GGI48_RS11700 2511035..2512348 - 1314 WP_179598412.1 precorrin-3B synthase -
GGI48_RS11705 2512480..2513694 + 1215 WP_016968231.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
GGI48_RS11710 2513788..2514885 + 1098 WP_047301443.1 cobalt-precorrin-5B (C(1))-methyltransferase -
GGI48_RS11715 2514882..2515610 + 729 WP_016968233.1 cobalt-precorrin-6A reductase -
GGI48_RS11720 2515794..2516096 + 303 WP_016968234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GGI48_RS11725 2516100..2516390 + 291 WP_179598414.1 putative addiction module antidote protein Antitoxin
GGI48_RS11730 2516490..2516888 + 399 WP_179598416.1 DUF2946 domain-containing protein -
GGI48_RS11735 2516953..2517432 + 480 WP_173655926.1 copper chaperone PCu(A)C -
GGI48_RS11740 2517488..2517898 + 411 WP_179598417.1 DUF2946 domain-containing protein -
GGI48_RS11745 2517987..2520119 + 2133 WP_179598419.1 TonB-dependent copper receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-91)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11605.34 Da        Isoelectric Point: 10.7824

>T170097 WP_016968234.1 NZ_CP060201:2515794-2516096 [Pseudomonas protegens]
MFIFEQTQAFTHWLLRLKDPQGKTRVLARIRAAQLGRFGDCEPVGDGVYEMRIHRGPGYRVYFSRRGNRIYLLLIGGDKS
TQKRDIQQARQLAHDLKSEG

Download         Length: 303 bp

>T170097 NZ_CP077082:c1819175-1818882 [Pseudomonas sp. OE 28.3]
GTGCGTTATTCGATCCAGCAAACCCAAGCCTTCACTCAATGGTGCTCGGCAATTCGCGATCTGCGAGCAAAAATCACCAT
TGCTCGACGTATCGAGCGAGCCAGTGTGGGCAATCTGGGGGATTTCAAGGTGCTGGGCGGCGGTGTTTCAGAGATGCGGA
TAGACGTAGGTGCAGGTTATCGCGTTTATTTCACCCTGCGCGGCAGGGAGGTTGTCATCTTGCTGGCAGGTGGCGACAAG
TCCTCACAAGAGGCCGATATCCGGCGAGCAAAAAAATTAGCAAAGGAGGTTTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10386.92 Da        Isoelectric Point: 5.8268

>AT170097 WP_179598414.1 NZ_CP060201:2516100-2516390 [Pseudomonas protegens]
MHTPVTRFDAAEYLKTPEDMVAYLDACFEEDAGDGKLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLNVSPA

Download         Length: 291 bp

>AT170097 NZ_CP077082:c1818879-1818571 [Pseudomonas sp. OE 28.3]
ATGACTCAAACACTGACGACATTTGATATGGCCGAGCTGCTCGACAGTGATGAGGCCATCAGCGAATACCTTTCTCAGGT
GCTGGCTGACGGTGACAACGAAGAGTTCCTTCGCGCCGTAGGCTACGTAGCCAAAGCCCGTGGCATGACAAAGATCGCCA
CGGATGCGGGCGTAGGGCGCGAGAGCTTGTACAAGGCATTTGCCCCGGGCGCAAAACCTCGTTTTGAAACGGTTCTGAAG
GTGCTTCACTCACTGGGCATTGATCTGTTGGCTCGGCCTGGGCATACCAGCAATTATTCGATTGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References