Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 65916..66718 Replicon plasmid pMDW2
Accession NZ_CP060199
Organism Aminobacter sp. MDW-2

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag H5P29_RS31445 Protein ID WP_185910464.1
Coordinates 66191..66718 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag H5P29_RS31440 Protein ID WP_154387124.1
Coordinates 65916..66194 (+) Length 93 a.a.

Genomic Context

H5P29_RS31440H5P29_RS31445H5P29_RS31450H5P29_RS31455H5P29_RS31460H5P29_RS31420H5P29_RS31425H5P29_RS31430H5P29_RS31435
Location: 65916..66194 (279 bp)
Type: Antitoxin
Protein ID: WP_154387124.1
Location: 66191..66718 (528 bp)
Type: Toxin
Protein ID: WP_185910464.1
Location: 67001..67963 (963 bp)
Type: Others
Protein ID: WP_154387125.1
Location: 67969..68679 (711 bp)
Type: Others
Protein ID: WP_154387126.1
Location: 68738..71389 (2652 bp)
Type: Others
Protein ID: WP_154387127.1
Location: 61235..62242 (1008 bp)
Type: Others
Protein ID: WP_154387121.1
Location: 62242..63435 (1194 bp)
Type: Others
Protein ID: WP_185910470.1
Location: 64200..64523 (324 bp)
Type: Others
Protein ID: Protein_69
Location: 64701..65816 (1116 bp)
Type: Others
Protein ID: WP_154387123.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H5P29_RS3142061235..62242-1008WP_154387121.1plasmid partitioning protein RepB-
H5P29_RS3142562242..63435-1194WP_185910470.1plasmid partitioning protein RepA-
H5P29_RS3143064200..64523-324Protein_69PIN domain-containing protein-
H5P29_RS3143564701..65816-1116WP_154387123.1site-specific integrase-
H5P29_RS3144065916..66194+279WP_154387124.1DUF1778 domain-containing proteinAntitoxin
H5P29_RS3144566191..66718+528WP_185910464.1GNAT family N-acetyltransferaseToxin
H5P29_RS3145067001..67963+963WP_154387125.1DUF1403 family protein-
H5P29_RS3145567969..68679+711WP_154387126.1SMC-Scp complex subunit ScpB-
H5P29_RS3146068738..71389+2652WP_154387127.1PD-(D/E)XK nuclease family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..157689157689


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18809.71 Da        Isoelectric Point: 8.2950

>T170094 WP_185910464.1 NZ_CP060199:66191-66718 [Aminobacter sp. MDW-2]
VNVPPWHEAAIARSHDRKAFDCGDVEMNGFLQRFARQGHEQNAVKTYCAVPDDAPTRVLGFYSLAPASVEHDAVPAAMTK
GMARHAVPGFLLARLAVDQSLAGRGLGGQLLLAAALRCIRVTVEVGGVLMIIDAKNERAANWYARYGAEPLKDRPLTLVV
PLATFAKALEATGHL

Download         Length: 528 bp

>T170094 NZ_CP077082:c1809938-1809654 [Pseudomonas sp. OE 28.3]
ATGCAGGTTGATTGGCTGAGGGCTGCCCTCAGGAATCTTGACGATGAAGCGGCCTACATTGCCGAAGAAAACCCGAAAGC
TGCCCATGAGTTCGTGCAGGCGATCTTGACCGGGCTTGAACATGTCGCTGAATTTCCGGCAATGGGCAAAGAAGGCAGAG
TGCCCGGCACGCGCGAATGGGTAGTGCCCCGATGGCCCTATATCGTTCCCTACCGTATTCGAGATGGCCGGTTACAGGTG
ATGCGAATTTTTCATACACGCCGCCAGCCACCCGCTTCCTGGTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10145.77 Da        Isoelectric Point: 10.8838

>AT170094 WP_154387124.1 NZ_CP060199:65916-66194 [Aminobacter sp. MDW-2]
MPRTALDDTDRMNIRVKPEVKARLLRAAALRHTDLTSFVTQSALREAETVIAEADAIKVSERDFGRILTLLDNPPKPNAR
LRAAAAALPKTL

Download         Length: 279 bp

>AT170094 NZ_CP077082:c1810167-1809928 [Pseudomonas sp. OE 28.3]
ATGTCTGTTATGTCTCTACGCATACCGGAAGACGTCGCCGACACGCTTGCCAGTCTCGCCAAGGCGACAGGGCGCAGCAA
ATCCTTTCTAGCCGTAGATGCATTACGCGAATACCTGACGCGTGAGGCCTGGCAAATAGAGGAAATTCAAAAAGCATTGA
AAGAAGCTGATGCGGGCGACTTTGCGACAGCGGCCGAAGTAAAAGCAGTCGCCGATAAATGGCGTAACAATGCAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References