Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 5416346..5418036 Replicon chromosome
Accession NZ_CP060197
Organism Aminobacter sp. MDW-2

Toxin (Protein)


Gene name HipA2 Uniprot ID -
Locus tag H5P29_RS26730 Protein ID WP_154385356.1
Coordinates 5416346..5417695 (-) Length 450 a.a.

Antitoxin (Protein)


Gene name HipB2 Uniprot ID -
Locus tag H5P29_RS26735 Protein ID WP_154385396.1
Coordinates 5417701..5418036 (-) Length 112 a.a.

Genomic Context

H5P29_RS26700H5P29_RS26705H5P29_RS26710H5P29_RS26715H5P29_RS26720H5P29_RS26725H5P29_RS26730H5P29_RS26735H5P29_RS26740H5P29_RS26745H5P29_RS26750
Location: 5411504..5412842 (1339 bp)
Type: Others
Protein ID: Protein_5286
Location: 5412839..5413528 (690 bp)
Type: Others
Protein ID: WP_154385358.1
Location: 5413525..5414505 (981 bp)
Type: Others
Protein ID: WP_067965104.1
Location: 5414502..5415650 (1149 bp)
Type: Others
Protein ID: WP_154385357.1
Location: 5415647..5415877 (231 bp)
Type: Others
Protein ID: WP_067965108.1
Location: 5416038..5416295 (258 bp)
Type: Others
Protein ID: WP_083948686.1
Location: 5416346..5417695 (1350 bp)
Type: Toxin
Protein ID: WP_154385356.1
Location: 5417701..5418036 (336 bp)
Type: Antitoxin
Protein ID: WP_154385396.1
Location: 5419061..5420317 (1257 bp)
Type: Others
Protein ID: WP_067965111.1
Location: 5420611..5422173 (1563 bp)
Type: Others
Protein ID: WP_067965113.1
Location: 5422271..5422729 (459 bp)
Type: Others
Protein ID: WP_067965115.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H5P29_RS267005411504..5412842+1339Protein_5286P-type conjugative transfer protein TrbL-
H5P29_RS267055412839..5413528+690WP_154385358.1conjugal transfer protein TrbF-
H5P29_RS267105413525..5414505+981WP_067965104.1P-type conjugative transfer protein TrbG-
H5P29_RS267155414502..5415650+1149WP_154385357.1TrbI/VirB10 family protein-
H5P29_RS267205415647..5415877+231WP_067965108.1DUF2274 domain-containing protein-
H5P29_RS267255416038..5416295+258WP_083948686.1AlpA family phage regulatory protein-
H5P29_RS267305416346..5417695-1350WP_154385356.1HipA domain-containing proteinToxin
H5P29_RS267355417701..5418036-336WP_154385396.1helix-turn-helix transcriptional regulatorAntitoxin
H5P29_RS267405419061..5420317-1257WP_067965111.1site-specific integrase-
H5P29_RS267455420611..5422173-1563WP_067965113.1glutamine-hydrolyzing GMP synthase-
H5P29_RS267505422271..5422729-459WP_067965115.1MarR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(8-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-106)


Sequences

Toxin        


Download         Length: 450 a.a.        Molecular weight: 49012.78 Da        Isoelectric Point: 5.5530

>T170092 WP_154385356.1 NZ_CP060197:c5417695-5416346 [Aminobacter sp. MDW-2]
VDLLALDVRLDGFDDPVGVFVRDERGAVAFGYNRRYLANPDAAPLSLSLPLVGGPYPDVAARAFFDNLLQERDGALTEVM
EREGLARDDIAGLLFHLGKDCAGALSVLPMGSPPAKVPGDYERDYVPIPPDRLAAIVEALHNRTRLPTGMEDPSPLAGVQ
SKIALTVLPDGRFAEPNPGSGAPTTHILKVPDQGHKRDARYEAEAMDLSRKLGMETAEATALPVGGIEALLVTRFDRGRD
RLGRVVRLHQEDFAQALGLPASMKYERRGREGRRFDVSGIRKILEQTVDPARAKEAFIQATIFDLLVGNADGHAKNFALL
YEPGGRVRLAPRYDILPTRLDDSLTDELPYSIGEAKTLDEVTPSALDAFFQALGIENAAGRRRLAQRYARDIAFALASHL
KALEKNEKRFADLIASNIRALLGALEIEIPDAARERDAFISKAGGWHMS

Download         Length: 1350 bp

>T170092 NZ_CP077081:c6038092-6037814 [Pseudomonas atacamensis]
ATGATCGTTAGCTTCAGATGTCCTGAAACCGAATACCTGTTCCGAAGTGGTAAAACCCGTTTCTGGTCAGCCATATTGAG
TGTCGCGGAACGTAAGCTGACGATGCTTGATGCGGCAGCTGCGTTGGCTGATCTCCGATCTCCTCCCGGAAATCGGCTCG
AGTCTCTGGGAGGCGATCGGAAGGGGCAATGCAGTATTCGTATCAACGCCCAATGGCGAATTTGCTTCGTCTGGGGCCTG
AATGGGCCCGAGGATGTTGAAATCGTCGATTATCACTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12209.83 Da        Isoelectric Point: 10.7725

>AT170092 WP_154385396.1 NZ_CP060197:c5418036-5417701 [Aminobacter sp. MDW-2]
MPQGVRVSLPHSVQDSYKQQNRATVDDNAIASRAIRDTEAEGLEVVSPSDLGLLVRRARETRHLSQQSFADLAGVGRRFL
SELENGKPTLELGKVLKVARTAGISLFARQR

Download         Length: 336 bp

>AT170092 NZ_CP077081:c6037806-6037501 [Pseudomonas atacamensis]
ATGACCAAGAATGGTATGCGTCCGGTCCATCCCGGCGAGATCCTCAAAGAGGAGTATCTGGAGCCTTTGAGCCTTACAGC
CGCTGCGTTGGCGAGAGCATTGAGCGTGTCTACTCCGACGGTGAACGATATCGTTCTACAGCGCCGGGGCATCAGCGCTG
ACATGGCTTTAAGACTTTCAATCTGTCTGGACACCACTCCTGAGTTTTGGCTGAACCTCCAATCGACCTACGATCTGCGA
AAAGCCGAAATTGAAAGAGGAACTGCAATCCGTGATCAGGTCGAGCGGCTGGCACATTGCGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References