Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-couple_hipB
Location 1317662..1318278 Replicon chromosome
Accession NZ_CP060138
Organism Rickettsia sp. Tillamook 23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H6P87_RS07055 Protein ID WP_202069426.1
Coordinates 1317662..1317922 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H6P87_RS07060 Protein ID WP_011271587.1
Coordinates 1317919..1318278 (+) Length 120 a.a.

Genomic Context

H6P87_RS07050H6P87_RS07055H6P87_RS07060H6P87_RS07070H6P87_RS07025H6P87_RS07030H6P87_RS07035H6P87_RS07040H6P87_RS07045H6P87_RS07065H6P87_RS07075H6P87_RS07080H6P87_RS07085
Location: 1317283..1317522 (240 bp)
Type: Others
Protein ID: WP_040256476.1
Location: 1317662..1317922 (261 bp)
Type: Toxin
Protein ID: WP_202069426.1
Location: 1317919..1318278 (360 bp)
Type: Antitoxin
Protein ID: WP_011271587.1
Location: 1319105..1319275 (171 bp)
Type: Others
Protein ID: WP_202069431.1
Location: 1312751..1313629 (879 bp)
Type: Others
Protein ID: WP_202069403.1
Location: 1313643..1314515 (873 bp)
Type: Others
Protein ID: WP_202069405.1
Location: 1314596..1315075 (480 bp)
Type: Others
Protein ID: WP_202069407.1
Location: 1315068..1316795 (1728 bp)
Type: Others
Protein ID: WP_202069420.1
Location: 1316792..1317118 (327 bp)
Type: Others
Protein ID: WP_202069423.1
Location: 1318401..1318847 (447 bp)
Type: Others
Protein ID: WP_202069428.1
Location: 1319478..1320746 (1269 bp)
Type: Others
Protein ID: WP_202070157.1
Location: 1321003..1321869 (867 bp)
Type: Others
Protein ID: WP_202069437.1
Location: 1322661..1323131 (471 bp)
Type: Others
Protein ID: Protein_1381
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H6P87_RS070251312751..1313629-879WP_202069403.1HEPN domain-containing protein-
H6P87_RS070301313643..1314515-873WP_202069405.1Rpn family recombination-promoting nuclease/putative transposase-
H6P87_RS070351314596..1315075-480WP_202069407.1SH3 domain-containing protein-
H6P87_RS070401315068..1316795-1728WP_202069420.1cation:proton antiporter-
H6P87_RS070451316792..1317118-327WP_202069423.1ribosome silencing factor-
H6P87_RS070501317283..1317522+240WP_040256476.1BolA family transcriptional regulator-
H6P87_RS070551317662..1317922+261WP_202069426.1type II toxin-antitoxin system RelE/ParE family toxinToxin
H6P87_RS070601317919..1318278+360WP_011271587.1helix-turn-helix transcriptional regulatorAntitoxin
H6P87_RS070651318401..1318847-447WP_202069428.1ferritin-like domain-containing protein-
H6P87_RS070701319105..1319275+171WP_202069431.1hypothetical protein-
H6P87_RS070751319478..1320746-1269WP_202070157.1autotransporter outer membrane beta-barrel domain-containing protein-
H6P87_RS070801321003..1321869-867WP_202069437.1hypothetical protein-
H6P87_RS070851322661..1323131-471Protein_1381hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

Cro/C1-type helix-turn-helix domain

(65-119)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10202.16 Da        Isoelectric Point: 10.6178

>T170040 WP_202069426.1 NZ_CP060138:1317662-1317922 [Rickettsia tillamookensis]
MQYKLSFSKTALKNLLKISINKRKAILEKLEQLKLNPYKENNNIKKLIGYDGYRLRIGDYRVIYRINKGKLEILVINVDV
RGEVYK

Download         Length: 261 bp

>T170040 NZ_CP077061:1038492-1038770 [Vibrio cholerae]
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGTGAGAAAATTTTCGAATTTCTCTACGACTTTAACCCAGCAGCGGC
TAAAAAAACGGATGAGCTCATAGAAGCCAAAGTCGAAAATTTGCTTGAGCAACCACTAATCGGTGTTCAGCGTGATGGCA
TTAGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13799.99 Da        Isoelectric Point: 6.9804

>AT170040 WP_011271587.1 NZ_CP060138:1317919-1318278 [Rickettsia tillamookensis]
MSNKHIIEYQGKPAFVVIPFNEYQELINKKQCITDETLYAEAIAKNEEYFPEDLVQKILNGENPIKVYREYRGLSQEQLA
IKIGKTKQYISFIEKGLRKGTIDTLKKLSTVLNVDLDML

Download         Length: 360 bp

>AT170040 NZ_CP077061:1038211-1038495 [Vibrio cholerae]
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGAAC
TCTTAGCGATGCTTGCCGTGAACTCACTGAACAATTAGCTGAGCAGCAACGCAAGGCATTATCTCACGATGCATGGCTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCAGTATTCATTGAACATGACATCGCCAAAGCACGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGCCACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References