Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 820726..821257 Replicon chromosome
Accession NZ_CP060138
Organism Rickettsia sp. Tillamook 23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H6P87_RS04390 Protein ID WP_202068378.1
Coordinates 820976..821257 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag H6P87_RS04385 Protein ID WP_202070119.1
Coordinates 820726..820989 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H6P87_RS04365 816075..816279 + 205 Protein_854 hypothetical protein -
H6P87_RS04370 816273..817637 + 1365 WP_202068374.1 hypothetical protein -
H6P87_RS04375 817634..817852 - 219 WP_202070172.1 hypothetical protein -
H6P87_RS04380 817877..820633 + 2757 WP_202068376.1 alkaline phosphatase -
H6P87_RS04385 820726..820989 + 264 WP_202070119.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H6P87_RS04390 820976..821257 + 282 WP_202068378.1 type II toxin-antitoxin system YafQ family toxin Toxin
H6P87_RS04395 821299..822204 + 906 WP_202068380.1 LD-carboxypeptidase -
H6P87_RS04400 822201..823106 + 906 WP_202068382.1 hydroxymethylbilane synthase -
H6P87_RS04405 823404..824519 + 1116 WP_202068384.1 hypothetical protein -
H6P87_RS04410 824723..825676 + 954 WP_202068391.1 N-acetylmuramoyl-L-alanine amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-73)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11022.95 Da        Isoelectric Point: 10.4157

>T170039 WP_202068378.1 NZ_CP060138:820976-821257 [Rickettsia tillamookensis]
MRTIKRTAQFKRDYKREKRRKHGINLDDILLKAVKYLVADITLPVHMRDHALIGNWKDCRDCHIKPDLVLIYRKPNTDTL
ELIRLGSHSELGF

Download         Length: 282 bp

>T170039 NZ_CP077061:77265-77582 [Vibrio cholerae]
ATGCAAAATAAACAATATAAGCTCAGCCAATTAGCCCAAGAGCACTTACTCAAGATTAAACACTACACCATTGAAAATTT
CGCTGAAGCGCAGTGGCAAAAATATAAGTCGACCTTGCTTTCAGGTTTCCAAACTCTTGCGGATAACCCAGGACTAGGAA
AAAGCTGTGAAGATATTTACCAAAATGGTTTTTACTTTCCAGTGGGGAAACACATGGCTTATTACACCAAAGAAGCAAAC
TTCATTCTCATTGTTGCGGTATTAGGGCAATCACAACTGCCCCAAAAGCATCTCAAACAGTCACGCTTTGTTTCTTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9488.02 Da        Isoelectric Point: 5.8235

>AT170039 WP_202070119.1 NZ_CP060138:820726-820989 [Rickettsia tillamookensis]
MSVGSIVRARINEDVKEEATVVLAAMGLTVSDAVRMLLFRVAREKALPFEPLIPNDETIKAMKAARSGKLVHVGNINNLL
SDLNEND

Download         Length: 264 bp

>AT170039 NZ_CP077061:77004-77246 [Vibrio cholerae]
ATGCACACACTAACAGCAAATGATGCTAAACGAAATTTTGGTGAACTTCTTCTAAGCGCACAACGCGAACCTGTCATCAT
CAGCAAAAACAGTAAGAATACTGTCGTTGTCATGTCCATTAAGGACTTTGAAGAACTTGAAGCAATGAAACTCGATTATC
TCAAACACTGCTTTGAGTCTGCTCAGAAAGACTTAGATAGTGGCAAAACCGTTGATGGTGCCACTTTTCTAAACACCCTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References