Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 21045..21579 Replicon plasmid unnamed2
Accession NZ_CP060126
Organism Sphingobium yanoikuyae strain A3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H3V42_RS33280 Protein ID WP_185708028.1
Coordinates 21045..21326 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H3V42_RS33285 Protein ID WP_185708030.1
Coordinates 21313..21579 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3V42_RS33255 17652..17957 + 306 WP_185708018.1 hypothetical protein -
H3V42_RS33260 17954..18352 + 399 WP_185708020.1 CopG family transcriptional regulator -
H3V42_RS33265 18352..19314 + 963 WP_185708022.1 tyrosine-type recombinase/integrase -
H3V42_RS33270 19356..20243 - 888 WP_185708024.1 aspartyl protease family protein -
H3V42_RS33275 20415..21035 - 621 WP_185708026.1 histidine phosphatase family protein -
H3V42_RS33280 21045..21326 - 282 WP_185708028.1 type II toxin-antitoxin system YafQ family toxin Toxin
H3V42_RS33285 21313..21579 - 267 WP_185708030.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H3V42_RS33290 22058..22699 + 642 WP_185708032.1 transcription elongation protein SprT -
H3V42_RS33295 22783..23439 + 657 WP_185708034.1 AAA family ATPase -
H3V42_RS33300 23436..23753 + 318 WP_185708036.1 hypothetical protein -
H3V42_RS33305 23811..24236 + 426 WP_185708064.1 GFA family protein -
H3V42_RS33310 24312..25424 - 1113 WP_185708038.1 replication initiator protein A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..54690 54690


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-81)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10726.16 Da        Isoelectric Point: 8.9188

>T170035 WP_185708028.1 NZ_CP060126:c21326-21045 [Sphingobium yanoikuyae]
MRTIDRSTRFKRDYKRELKGRHRATLDADFQPVLVALATDTPLDPKYRDHDLSGDWAGYRDCHIKPDLVLIYAKPDDATL
RLARLGSHSEVFG

Download         Length: 282 bp

>T170035 NZ_CP077061:58702-58980 [Vibrio cholerae]
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGTGAGAAAATTTTCGAATTTCTCTACGACTTTAACCCAGCAGCGGC
TAAAAAAACGGATGAGCTCATAGAAGCCAAAGTCGAAAATTTGCTTGAGCAACCACTAATCGGTGTTCAGCGTGATGGCA
TTAGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9432.88 Da        Isoelectric Point: 5.8296

>AT170035 WP_185708030.1 NZ_CP060126:c21579-21313 [Sphingobium yanoikuyae]
MAVSDTYVRARIDNTTKERATAALGAMGLSISDAIRLLMLRIADERRLPFEVKVPNAATREAMAELAAGKGAKFASVEAL
MADLHADD

Download         Length: 267 bp

>AT170035 NZ_CP077061:58421-58705 [Vibrio cholerae]
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGAAC
TCTTAGCGATGCTTGCCGTGAACTCACTGAACAATTAGCTGAGCAGCAACGCAAGGCATTATCTCACGATGCATGGCTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCAGTATTCATTGAACATGACATCGCCAAAGCACGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGCCACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References