170033

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 5549408..5550432 Replicon chromosome
Accession NZ_CP060122
Organism Sphingobium yanoikuyae strain A3

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag H3V42_RS26565 Protein ID WP_185704750.1
Coordinates 5549408..5549986 (-) Length 193 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag H3V42_RS26570 Protein ID WP_185704751.1
Coordinates 5549983..5550432 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3V42_RS26535 5544664..5545596 - 933 WP_185704739.1 Abi family protein -
H3V42_RS26540 5545761..5547224 - 1464 WP_185704741.1 type I restriction-modification system subunit M -
H3V42_RS26545 5547221..5547826 - 606 WP_185704743.1 hypothetical protein -
H3V42_RS26550 5547823..5548623 - 801 WP_185704745.1 hypothetical protein -
H3V42_RS26555 5548647..5548856 + 210 WP_185704747.1 hypothetical protein -
H3V42_RS26560 5548813..5549325 + 513 WP_185704749.1 DUF3883 domain-containing protein -
H3V42_RS26565 5549408..5549986 - 579 WP_185704750.1 PIN domain-containing protein Toxin
H3V42_RS26570 5549983..5550432 - 450 WP_185704751.1 helix-turn-helix domain-containing protein Antitoxin
H3V42_RS26575 5550914..5552740 + 1827 Protein_5250 ParB/RepB/Spo0J family partition protein -
H3V42_RS26580 5553157..5554071 + 915 WP_185704753.1 DUF1738 domain-containing protein -
H3V42_RS26585 5554064..5554267 + 204 WP_185704755.1 hypothetical protein -
H3V42_RS26590 5554346..5555275 + 930 WP_185704757.1 HEPN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(10-116)

Antitoxin

SinI-like, DNA-binding domain

(80-126)


Sequences

Toxin        


Download         Length: 193 a.a.        Molecular weight: 21406.50 Da        Isoelectric Point: 4.6805

>T170033 WP_185704750.1 NZ_CP060122:c5549986-5549408 [Sphingobium yanoikuyae]
MSDIADRFVVILNANVLYPFRVRDTLLRFAEAGLFRARWSPTIMDEWTRNLLAKRPDLESSIRSQIAAMERAFPESCVSG
AEGLIPALELPDANDRHVLATAIRAGAEHIVTENLKDFPDEALAPFGITTVTPDDFLSSTFELYPGEALSTLRAMRRDYG
NPPFSPGEFIFELQGKGLPKLASMLKEHIDLL

Download         Length: 579 bp

>T170033 NZ_CP077061:36553-36870 [Vibrio cholerae]
ATGCAAAATAAACAATATAAGCTCAGCCAATTAGCCCAAGAGCACTTACTCAAGATTAAACACTACACCATTGAAAATTT
CGCTGAAGCGCAGTGGCAAAAATATAAGTCGACCTTGCTTTCAGGTTTCCAAACTCTTGCGGATAACCCAGGACTAGGAA
AAAGCTGTGAAGATATTTACCAAAATGGTTTTTACTTTCCAGTGGGGAAACACATGGCTTATTACACCAAAGAAGCAAAC
TTCATTCTCATTGTTGCGGTATTAGGGCAATCACAACTGCCCCAAAAGCATCTCAAACAGTCACGCTTTGTTTCTTAG

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16341.66 Da        Isoelectric Point: 5.6763

>AT170033 WP_185704751.1 NZ_CP060122:c5550432-5549983 [Sphingobium yanoikuyae]
MSEQALSERPPTENEVRAASEAARLLAKALTPAGLPISVEKNGDQFQLELPAPLGQLILDVLTHVGRGEMITLVPYGAEL
TTKEAADLLNVSRPFLVKLLDEGVIGHHKVGSHRRIRASELLGYKAKRDEERRAALTELQRLGQEFDAD

Download         Length: 450 bp

>AT170033 NZ_CP077061:36292-36534 [Vibrio cholerae]
ATGCACACACTAACAGCAAATGATGCTAAACGAAATTTTGGTGAACTTCTTCTAAGCGCACAACGCGAACCTGTCATCAT
CAGCAAAAACAGTAAGAATACTGTCGTTGTCATGTCCATTAAGGACTTTGAAGAACTTGAAGCAATGAAACTCGATTATC
TCAAACACTGCTTTGAGTCTGCTCAGAAAGACTTAGATAGTGGCAAAACCGTTGATGGTGCCACTTTTCTAAACACCCTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References