Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4319131..4319576 Replicon chromosome
Accession NZ_CP060122
Organism Sphingobium yanoikuyae strain A3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H3V42_RS20585 Protein ID WP_185703711.1
Coordinates 4319298..4319576 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H3V42_RS20580 Protein ID WP_010336649.1
Coordinates 4319131..4319301 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3V42_RS20570 4314921..4317857 + 2937 WP_185703707.1 excinuclease ABC subunit UvrA -
H3V42_RS20575 4318344..4318955 - 612 WP_185703709.1 hypothetical protein -
H3V42_RS20580 4319131..4319301 + 171 WP_010336649.1 hypothetical protein Antitoxin
H3V42_RS20585 4319298..4319576 + 279 WP_185703711.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H3V42_RS20590 4319714..4320868 + 1155 WP_185703713.1 hypothetical protein -
H3V42_RS20595 4321072..4321287 + 216 WP_004207726.1 cold-shock protein -
H3V42_RS20600 4321350..4321952 - 603 WP_010336652.1 hypothetical protein -
H3V42_RS20605 4322089..4322295 + 207 WP_010336653.1 hypothetical protein -
H3V42_RS20610 4322490..4322858 + 369 WP_010336654.1 glycine zipper 2TM domain-containing protein -
H3V42_RS20615 4322922..4323854 - 933 WP_010336655.1 FAD-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10472.04 Da        Isoelectric Point: 6.9872

>T170030 WP_185703711.1 NZ_CP060122:4319298-4319576 [Sphingobium yanoikuyae]
MTLPVVWDDEAETALLTILDYIGPRNKVAAERLYAAIRHTADNLPNHPYAHRPGRMSGTREAVVHPNYILIYRVAIEAIE
ILTLVHARQQYP

Download         Length: 279 bp

>T170030 NZ_CP077061:c12683-12351 [Vibrio cholerae]
ATGAAAAGTGTATTTGTCGAATCAACAATTTTTGAAAAGTACCGAGATGAATATCTCAGTGATGAGGAGTATAGGCTCTT
TCAAGCAGAGCTAATGCTAAACCCCAAGCTGGGTGATGTGATTCAAGGTACTGGCGGTTTGCGAAAAATTCGAGTTGCGA
GTAAAGGCAAGGGAAAGCGTGGTGGTTCACGGATTATCTATTACTTTCTCGATGAAAAGAGGCGTTTCTATTTGCTAACC
ATTTACGGCAAAAATGAAATGTCTGACTTGAATGCAAATCAAAGGAAACAACTAATGGCTTTTATGGAGGCGTGGCGCAA
TGAGCAATCGTGA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6238.14 Da        Isoelectric Point: 7.2019

>AT170030 WP_010336649.1 NZ_CP060122:4319131-4319301 [Sphingobium yanoikuyae]
MTKLTPIESEFATTEDAEAHDAWVRAKVERALASTKPRIPHDAVMAKAQAVLDKYK

Download         Length: 171 bp

>AT170030 NZ_CP077061:c12364-12050 [Vibrio cholerae]
ATGAGCAATCGTGATTTATTTGCAGAGTTAAGCTCAGCTCTTGTTGAGGCTAAGCAGCATTCAGAAGGTAAGCTTACTCT
GAAAACACATCATGTGAATGATGTGGGTGAGTTGAACATCTCACCGGATGAAATCGTGAGTATTCGCGAGCAGTTCAATA
TGTCCCGCGGAGTCTTCGCGCGGTTACTTCATACGTCTTCGCGCACATTAGAAAACTGGGAACAAGGTCGTAGTGTGCCA
AATGGTCAAGCGGTCACTCTTTTAAAGTTAGTACAGCGTCATCCAGAAACGTTGTCACACATAGCCGAGCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References