Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3289227..3289879 Replicon chromosome
Accession NZ_CP060120
Organism Janibacter sp. YB324

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H7A72_RS16165 Protein ID WP_084451100.1
Coordinates 3289227..3289619 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H7A72_RS16170 Protein ID WP_185221154.1
Coordinates 3289616..3289879 (-) Length 88 a.a.

Genomic Context

H7A72_RS16145H7A72_RS16155H7A72_RS16160H7A72_RS16175H7A72_RS16180H7A72_RS16185H7A72_RS16140H7A72_RS16150H7A72_RS16165H7A72_RS16170H7A72_RS16190
Location: 3285613..3286227 (615 bp)
Type: Others
Protein ID: WP_185221152.1
Location: 3287269..3287700 (432 bp)
Type: Others
Protein ID: WP_084451101.1
Location: 3287697..3289217 (1521 bp)
Type: Others
Protein ID: WP_185221153.1
Location: 3290017..3291183 (1167 bp)
Type: Others
Protein ID: WP_185221155.1
Location: 3291193..3291963 (771 bp)
Type: Others
Protein ID: WP_185221156.1
Location: 3291965..3292990 (1026 bp)
Type: Others
Protein ID: WP_072625985.1
Location: 3285089..3285481 (393 bp)
Type: Others
Protein ID: WP_185221151.1
Location: 3286314..3287072 (759 bp)
Type: Others
Protein ID: WP_185222428.1
Location: 3289227..3289619 (393 bp)
Type: Toxin
Protein ID: WP_084451100.1
Location: 3289616..3289879 (264 bp)
Type: Antitoxin
Protein ID: WP_185221154.1
Location: 3293012..3294235 (1224 bp)
Type: Others
Protein ID: WP_185221157.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H7A72_RS161403285089..3285481-393WP_185221151.1hypothetical protein-
H7A72_RS161453285613..3286227+615WP_185221152.1hypothetical protein-
H7A72_RS161503286314..3287072-759WP_185222428.1MerR family transcriptional regulator-
H7A72_RS161553287269..3287700+432WP_084451101.1hypothetical protein-
H7A72_RS161603287697..3289217+1521WP_185221153.1multicopper oxidase family protein-
H7A72_RS161653289227..3289619-393WP_084451100.1type II toxin-antitoxin system VapC family toxinToxin
H7A72_RS161703289616..3289879-264WP_185221154.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
H7A72_RS161753290017..3291183+1167WP_185221155.1phytanoyl-CoA dioxygenase family protein-
H7A72_RS161803291193..3291963+771WP_185221156.1SDR family oxidoreductase-
H7A72_RS161853291965..3292990+1026WP_072625985.1Gfo/Idh/MocA family oxidoreductase-
H7A72_RS161903293012..3294235-1224WP_185221157.1FAD-dependent oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(1-86)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14076.92 Da        Isoelectric Point: 4.5860

>T169997 WP_084451100.1 NZ_CP060120:c3289619-3289227 [Janibacter sp. YB324]
VIVDTSVLVCIHDGEPEARRYLEVLLDEPSPRISAGSLLEASIVLDARQPLRTSRRLDRLVADLRLDVVPVDEQQVSAAR
AAYRDYGKGSGHAAGLNFGDCFAYALAATTGEPLLFKGDDFTHTDVLPVV

Download         Length: 393 bp

>T169997 NZ_CP076851:c2476350-2475790 [Mycobacterium avium subsp. hominissuis]
GTGAGCGAAGCCCTCGATGAAGGGCTCGTCCAACGCATCGACGCACGCGGCACAACAGAGTGGTCGGGAACGTGCTACCG
CTATACCGGCGCGCATCGTGACGCCTTGTCCGGGGAGGGGGCACGCAGATTCGGAGGCAGGTGGAATCCACCCCTACTTT
TTCCGGCGATCTATCTTGCTGACTCCGCCCAGGCCTGCATGGTTGAGGTGGAACGGGTAGCGCAAGCGGCCTCAACGACC
GCAGAGAAGATGCTCGAGGCGACCTACCGACTGCACACCATCGATGTAACGGACCTGGCCGTTCTCGATCTGCGCACCCC
AGACGCCCGCGAAGCGGTAGGGCTCGAGAACGATGACATCTACGGCGATGACTGGTCAGCGTGCCAGGCGGTAGGGCACG
CAGCATGGTTCCTGCACATGCAAGGCGTCCTGGTGCCCGCGGCGGGCGGTGTCGGCGTAGTTGTCACCGCGTATGAACAA
CGAACCCGTCCAGGTCAACTACAGCTGCGACAAAGCGTCGATCTGACGCCTGTCCTTTACCAAGAACTCCGAGCCACCTA
A

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9933.00 Da        Isoelectric Point: 4.9057

>AT169997 WP_185221154.1 NZ_CP060120:c3289879-3289616 [Janibacter sp. YB324]
MGLNIKNQRVHDLAREVAQRTGTTQTSAIEEALQRRLEALRAADDDDARRRRLLRLMDEIESDTTAADRARTAQIQEELY
DDRGLPA

Download         Length: 264 bp

>AT169997 NZ_CP076851:c2476688-2476347 [Mycobacterium avium subsp. hominissuis]
ATGGGAGTAAACGCGCTCGCCTCGACGGTGTCGGGTGCGATCGAGCGCTTGGGATTGACCTACGAGGAAGTCGGCGAAAT
CGTCGATGCCTCCCCGCGCTCCGTGGCGCGATGGACCGCAGGTCAGGTAGTTCCTCAACGTCTCAACAAGCAACGACTAA
TCGAGCTGGCCTATGTCGCCGACGCCCTGGCGGAAGTGTTGCCGCGTGACCAGGCGAATGTGTGGATGTTTTCGCCGAAT
CGATTACTAGAACACCGCAAGCCTGCCGACCTCGTGCGAGACGGCGAATACCAACGCGTGTTGGCGCTCATCGACGCGAT
GGCGGAGGGAGTGTTCGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References