Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2377057..2377291 | Replicon | chromosome |
| Accession | NZ_CP060117 | ||
| Organism | Shigella sonnei strain UKMCC_1015 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2377187..2377290 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2377057..2377291 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HYI41_RS11660 | 2373612..2374274 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| HYI41_RS11665 | 2374298..2374954 | - | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| HYI41_RS11670 | 2375056..2375286 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HYI41_RS11675 | 2375425..2375799 | + | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| HYI41_RS11680 | 2375803..2376675 | + | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| HYI41_RS11685 | 2376688..2377029 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2377057..2377291 | - | 235 | - | - | Antitoxin |
| - | 2377187..2377290 | + | 104 | - | - | Toxin |
| HYI41_RS11690 | 2377422..2378498 | - | 1077 | WP_140046268.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| HYI41_RS11700 | 2379375..2380532 | - | 1158 | Protein_2269 | IS3-like element IS600 family transposase | - |
| HYI41_RS11705 | 2380595..2380711 | - | 117 | Protein_2270 | host-nuclease inhibitor Gam family protein | - |
| HYI41_RS11710 | 2380689..2381009 | - | 321 | WP_241556168.1 | exodeoxyribonuclease VIII | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 2371555..2405759 | 34204 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T169981 NZ_CP060117:2377187-2377290 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT169981 NZ_CP060117:c2377291-2377057 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGATAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGATAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
