Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/RHH(antitoxin) |
| Location | 3554162..3554703 | Replicon | chromosome |
| Accession | NZ_CP060092 | ||
| Organism | Teredinibacter purpureus strain Bs12 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | H5647_RS15575 | Protein ID | WP_045856568.1 |
| Coordinates | 3554401..3554703 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | - |
| Locus tag | H5647_RS15570 | Protein ID | WP_045859830.1 |
| Coordinates | 3554162..3554404 (+) | Length | 81 a.a. |
Genomic Context
Location: 3549548..3550618 (1071 bp)
Type: Others
Protein ID: WP_052691964.1
Type: Others
Protein ID: WP_052691964.1
Location: 3554162..3554404 (243 bp)
Type: Antitoxin
Protein ID: WP_045859830.1
Type: Antitoxin
Protein ID: WP_045859830.1
Location: 3554401..3554703 (303 bp)
Type: Toxin
Protein ID: WP_045856568.1
Type: Toxin
Protein ID: WP_045856568.1
Location: 3550870..3551232 (363 bp)
Type: Others
Protein ID: WP_045859824.1
Type: Others
Protein ID: WP_045859824.1
Location: 3551435..3552570 (1136 bp)
Type: Others
Protein ID: Protein_3082
Type: Others
Protein ID: Protein_3082
Location: 3553181..3553546 (366 bp)
Type: Others
Protein ID: WP_045859827.1
Type: Others
Protein ID: WP_045859827.1
Location: 3553663..3553995 (333 bp)
Type: Others
Protein ID: WP_045859828.1
Type: Others
Protein ID: WP_045859828.1
Location: 3554803..3555183 (381 bp)
Type: Others
Protein ID: WP_045859526.1
Type: Others
Protein ID: WP_045859526.1
Location: 3555301..3555894 (594 bp)
Type: Others
Protein ID: WP_045858604.1
Type: Others
Protein ID: WP_045858604.1
Location: 3556025..3556603 (579 bp)
Type: Others
Protein ID: WP_045859833.1
Type: Others
Protein ID: WP_045859833.1
Location: 3558110..3558499 (390 bp)
Type: Others
Protein ID: WP_045859837.1
Type: Others
Protein ID: WP_045859837.1
Location: 3558610..3559377 (768 bp)
Type: Others
Protein ID: WP_045858854.1
Type: Others
Protein ID: WP_045858854.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H5647_RS15545 | 3549548..3550618 | + | 1071 | WP_052691964.1 | transposase | - |
| H5647_RS15550 | 3550870..3551232 | - | 363 | WP_045859824.1 | hypothetical protein | - |
| H5647_RS15555 | 3551435..3552570 | - | 1136 | Protein_3082 | IS3 family transposase | - |
| H5647_RS15560 | 3553181..3553546 | - | 366 | WP_045859827.1 | hypothetical protein | - |
| H5647_RS15565 | 3553663..3553995 | - | 333 | WP_045859828.1 | hypothetical protein | - |
| H5647_RS15570 | 3554162..3554404 | + | 243 | WP_045859830.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
| H5647_RS15575 | 3554401..3554703 | + | 303 | WP_045856568.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| H5647_RS15580 | 3554803..3555183 | - | 381 | WP_045859526.1 | hypothetical protein | - |
| H5647_RS15585 | 3555301..3555894 | - | 594 | WP_045858604.1 | hypothetical protein | - |
| H5647_RS15590 | 3556025..3556603 | - | 579 | WP_045859833.1 | plasmid pRiA4b ORF-3 family protein | - |
| H5647_RS15595 | 3558110..3558499 | - | 390 | WP_045859837.1 | tetratricopeptide repeat protein | - |
| H5647_RS15600 | 3558610..3559377 | - | 768 | WP_045858854.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 3553076..3567535 | 14459 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11766.49 Da Isoelectric Point: 10.5642
>T169955 WP_045856568.1 NZ_CP060092:3554401-3554703 [Teredinibacter purpureus]
MSAFTLTRRAKTDLKSIAKFTEKRWGREQRYIYIKQFDDTFHVLSNTPEIGNNCNHIKENYQRFPQGSHIIFYRIATQGS
IQIIRILHKNMDVLSKFGGS
MSAFTLTRRAKTDLKSIAKFTEKRWGREQRYIYIKQFDDTFHVLSNTPEIGNNCNHIKENYQRFPQGSHIIFYRIATQGS
IQIIRILHKNMDVLSKFGGS
Download Length: 303 bp
>T169955 NZ_CP076817:c580854-580672 [Acinetobacter baumannii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAAAAAGCGGGTCTAAATTGA
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAAAAAGCGGGTCTAAATTGA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8826.72 Da Isoelectric Point: 4.3296
>AT169955 WP_045859830.1 NZ_CP060092:3554162-3554404 [Teredinibacter purpureus]
MAKNTSMTLGEHFDGFISHQIQSGRYGSASEVIRAGLRVLEDKESKLDVLRQMLADGEESGTADYSYDSLMSELDAESHI
MAKNTSMTLGEHFDGFISHQIQSGRYGSASEVIRAGLRVLEDKESKLDVLRQMLADGEESGTADYSYDSLMSELDAESHI
Download Length: 243 bp
>AT169955 NZ_CP076817:c580579-580175 [Acinetobacter baumannii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG