Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3554162..3554703 Replicon chromosome
Accession NZ_CP060092
Organism Teredinibacter purpureus strain Bs12

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H5647_RS15575 Protein ID WP_045856568.1
Coordinates 3554401..3554703 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag H5647_RS15570 Protein ID WP_045859830.1
Coordinates 3554162..3554404 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5647_RS15545 3549548..3550618 + 1071 WP_052691964.1 transposase -
H5647_RS15550 3550870..3551232 - 363 WP_045859824.1 hypothetical protein -
H5647_RS15555 3551435..3552570 - 1136 Protein_3082 IS3 family transposase -
H5647_RS15560 3553181..3553546 - 366 WP_045859827.1 hypothetical protein -
H5647_RS15565 3553663..3553995 - 333 WP_045859828.1 hypothetical protein -
H5647_RS15570 3554162..3554404 + 243 WP_045859830.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
H5647_RS15575 3554401..3554703 + 303 WP_045856568.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5647_RS15580 3554803..3555183 - 381 WP_045859526.1 hypothetical protein -
H5647_RS15585 3555301..3555894 - 594 WP_045858604.1 hypothetical protein -
H5647_RS15590 3556025..3556603 - 579 WP_045859833.1 plasmid pRiA4b ORF-3 family protein -
H5647_RS15595 3558110..3558499 - 390 WP_045859837.1 tetratricopeptide repeat protein -
H5647_RS15600 3558610..3559377 - 768 WP_045858854.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 3553076..3567535 14459


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(4-70)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11766.49 Da        Isoelectric Point: 10.5642

>T169955 WP_045856568.1 NZ_CP060092:3554401-3554703 [Teredinibacter purpureus]
MSAFTLTRRAKTDLKSIAKFTEKRWGREQRYIYIKQFDDTFHVLSNTPEIGNNCNHIKENYQRFPQGSHIIFYRIATQGS
IQIIRILHKNMDVLSKFGGS

Download         Length: 303 bp

>T169955 NZ_CP076817:c580854-580672 [Acinetobacter baumannii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAAAAAGCGGGTCTAAATTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8826.72 Da        Isoelectric Point: 4.3296

>AT169955 WP_045859830.1 NZ_CP060092:3554162-3554404 [Teredinibacter purpureus]
MAKNTSMTLGEHFDGFISHQIQSGRYGSASEVIRAGLRVLEDKESKLDVLRQMLADGEESGTADYSYDSLMSELDAESHI

Download         Length: 243 bp

>AT169955 NZ_CP076817:c580579-580175 [Acinetobacter baumannii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References