Detailed information of TA system TA169938

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 287196..288121
• Replicon: chromosome
• Accession: NZ_CP060086
• Organism: Pseudomonas aeruginosa strain JNQH-PA57

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: H5409_RS01310
• Protein ID: WP_170868726.1
• Coordinates: 287795..288121 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: H5409_RS01305
• Protein ID: WP_003111464.1
• Coordinates: 287196..287723 (+)
• Length: 176 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H5409_RS01280	282223..282510	-	288	WP_023443569.1	hypothetical protein	-
H5409_RS01285	282602..283078	-	477	WP_009315008.1	MarR family transcriptional regulator	-
H5409_RS01290	283119..284609	-	1491	WP_003137133.1	UbiD family decarboxylase	-
H5409_RS01295	284743..285429	-	687	WP_003106170.1	DUF1275 domain-containing protein	-
H5409_RS01300	285593..286525	-	933	WP_003084116.1	hypothetical protein	-
H5409_RS01305	287196..287723	+	528	WP_003111464.1	SocA family protein	Antitoxin
H5409_RS01310	287795..288121	+	327	WP_170868726.1	hypothetical protein	Toxin
H5409_RS01320	289563..291005	-	1443	WP_003133043.1	DUF2875 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (18-128)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12366.33 Da
• Isoelectric Point: 8.6957

>T169938 WP_170868726.1 NZ_CP060086:287795-288121 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Nucleotide

• Length: 327 bp

>T169938 NZ_CP076801:c1708744-1708355 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAGTAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTAATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 176 a.a.
• Molecular weight: 20237.82 Da
• Isoelectric Point: 5.7215

>AT169938 WP_003111464.1 NZ_CP060086:287196-287723 [Pseudomonas aeruginosa]
MAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAWISPLVDHEVR
LVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQSEELAEIKARD
LAERRRHGRKLSEFI

Nucleotide

• Length: 528 bp

>AT169938 NZ_CP076801:c1709008-1708751 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCATTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA