Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 287196..288121 Replicon chromosome
Accession NZ_CP060086
Organism Pseudomonas aeruginosa strain JNQH-PA57

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag H5409_RS01310 Protein ID WP_170868726.1
Coordinates 287795..288121 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag H5409_RS01305 Protein ID WP_003111464.1
Coordinates 287196..287723 (+) Length 176 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5409_RS01280 282223..282510 - 288 WP_023443569.1 hypothetical protein -
H5409_RS01285 282602..283078 - 477 WP_009315008.1 MarR family transcriptional regulator -
H5409_RS01290 283119..284609 - 1491 WP_003137133.1 UbiD family decarboxylase -
H5409_RS01295 284743..285429 - 687 WP_003106170.1 DUF1275 domain-containing protein -
H5409_RS01300 285593..286525 - 933 WP_003084116.1 hypothetical protein -
H5409_RS01305 287196..287723 + 528 WP_003111464.1 SocA family protein Antitoxin
H5409_RS01310 287795..288121 + 327 WP_170868726.1 hypothetical protein Toxin
H5409_RS01320 289563..291005 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(18-128)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12366.33 Da        Isoelectric Point: 8.6957

>T169938 WP_170868726.1 NZ_CP060086:287795-288121 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

>T169938 NZ_CP076801:c1708744-1708355 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAGTAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTAATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 176 a.a.        Molecular weight: 20237.82 Da        Isoelectric Point: 5.7215

>AT169938 WP_003111464.1 NZ_CP060086:287196-287723 [Pseudomonas aeruginosa]
MAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAWISPLVDHEVR
LVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQSEELAEIKARD
LAERRRHGRKLSEFI

Download         Length: 528 bp

>AT169938 NZ_CP076801:c1709008-1708751 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCATTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References