Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 685101..685642 Replicon chromosome
Accession NZ_CP060084
Organism Teredinibacter haidensis strain Bs08

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H5715_RS02780 Protein ID WP_045856568.1
Coordinates 685101..685403 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag H5715_RS02785 Protein ID WP_045859830.1
Coordinates 685400..685642 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5715_RS02765 680213..680830 + 618 WP_075184542.1 hypothetical protein -
H5715_RS02770 680965..681486 + 522 WP_075184543.1 hypothetical protein -
H5715_RS02775 682910..683347 + 438 WP_139309887.1 DUF1311 domain-containing protein -
H5715_RS02780 685101..685403 - 303 WP_045856568.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5715_RS02785 685400..685642 - 243 WP_045859830.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
H5715_RS02790 686220..686681 + 462 WP_139309907.1 hypothetical protein -
H5715_RS02795 686777..687199 + 423 WP_185906528.1 lipocalin family protein -
H5715_RS02800 687924..688862 + 939 WP_075187525.1 hypothetical protein -
H5715_RS02805 688855..689976 + 1122 WP_075187526.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 671739..711250 39511
- inside Integron - - 666923..710397 43474


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(4-70)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11766.49 Da        Isoelectric Point: 10.5642

>T169932 WP_045856568.1 NZ_CP060084:c685403-685101 [Teredinibacter haidensis]
MSAFTLTRRAKTDLKSIAKFTEKRWGREQRYIYIKQFDDTFHVLSNTPEIGNNCNHIKENYQRFPQGSHIIFYRIATQGS
IQIIRILHKNMDVLSKFGGS

Download         Length: 303 bp

>T169932 NZ_CP076739:c2791470-2791288 [Acinetobacter baumannii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGACGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
CAAACACCCAACCAAAAAGGGATTAGTTACTATCCCGCATCCTAAAAAGGATTTACCAAGCGGAACTGTTAAAAGCATTT
TGAAGCAAGCGGGTCTAAAGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8826.72 Da        Isoelectric Point: 4.3296

>AT169932 WP_045859830.1 NZ_CP060084:c685642-685400 [Teredinibacter haidensis]
MAKNTSMTLGEHFDGFISHQIQSGRYGSASEVIRAGLRVLEDKESKLDVLRQMLADGEESGTADYSYDSLMSELDAESHI

Download         Length: 243 bp

>AT169932 NZ_CP076739:c2791223-2790819 [Acinetobacter baumannii]
ATGTTGTATCCAATTGCTATCGAGAGAGGTACAGACACCGAGGCCTTTGGTGTCACCGTTCCAGATATTCCAGGATGTTT
TAGCGCAGGCGATACATTAGAGGAAGCTATCGAGAACGTTAAAGAGGCAATTTCTGGCCACTTAGAAATCCTTGCTGAAG
ATGGAGAAGAAATTCCATTAGCATCTGACTTAGCAAAATTTGTAGATGATCCAGATTATAAAGGCATGATCTGGGCTGTT
ACTGAGGTGGATGTTAGTCGTTATCTTGGTAAGCCTGAAAAAATCAACGTAACTTTACCTAGCCGTTTAATTCGCAAGAT
TGATGATAATGTAGGTAAAGATAAAAGATTTAAAACTCGTTCTGCTTTTTTGGCCGCTGGTGCTGAAAAGCTACTACATG
CTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References