Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2239921..2240192 Replicon chromosome
Accession NZ_CP060083
Organism Escherichia coli strain G1/2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2240051..2240154 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2239921..2240192 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4P46_RS10795 2236476..2237138 - 663 WP_000944256.1 exodeoxyribonuclease X -
H4P46_RS10800 2237162..2237818 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H4P46_RS10805 2237920..2238150 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H4P46_RS10810 2238289..2238663 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H4P46_RS10815 2238667..2239539 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H4P46_RS10820 2239552..2239893 + 342 WP_000976476.1 YebY family protein -
- 2239921..2240192 - 272 - - Antitoxin
- 2240051..2240154 + 104 - - Toxin
H4P46_RS10825 2240289..2240945 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H4P46_RS10830 2240946..2241137 - 192 WP_000457842.1 YebW family protein -
H4P46_RS10835 2241242..2241478 - 237 WP_001295499.1 DUF1480 family protein -
H4P46_RS10840 2241596..2243035 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2155853..2256032 100179


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T169914 NZ_CP060083:2240051-2240154 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT169914 NZ_CP060083:c2240192-2239921 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References