Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1949662..1949933 Replicon chromosome
Accession NZ_CP060073
Organism Escherichia coli strain G4/9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1949792..1949895 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1949662..1949933 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4P48_RS09185 1946217..1946879 - 663 WP_000944258.1 exodeoxyribonuclease X -
H4P48_RS09190 1946903..1947559 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H4P48_RS09195 1947661..1947891 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H4P48_RS09200 1948030..1948404 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H4P48_RS09205 1948408..1949280 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
H4P48_RS09210 1949293..1949634 + 342 WP_000976472.1 YebY family protein -
- 1949662..1949933 - 272 - - Antitoxin
- 1949792..1949895 + 104 - - Toxin
H4P48_RS09215 1950030..1950686 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
H4P48_RS09220 1950687..1950878 - 192 WP_001338167.1 YebW family protein -
H4P48_RS09225 1950983..1951219 - 237 WP_001338166.1 DUF1480 family protein -
H4P48_RS09230 1951337..1952776 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T169866 NZ_CP060073:1949792-1949895 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT169866 NZ_CP060073:c1949933-1949662 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References