Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2252724..2252995 Replicon chromosome
Accession NZ_CP060057
Organism Escherichia coli strain G8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2252854..2252957 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2252724..2252995 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4P51_RS10855 2249279..2249941 - 663 WP_000944256.1 exodeoxyribonuclease X -
H4P51_RS10860 2249965..2250621 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H4P51_RS10865 2250723..2250953 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H4P51_RS10870 2251092..2251466 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H4P51_RS10875 2251470..2252342 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H4P51_RS10880 2252355..2252696 + 342 WP_000976476.1 YebY family protein -
- 2252724..2252995 - 272 - - Antitoxin
- 2252854..2252957 + 104 - - Toxin
H4P51_RS10885 2253092..2253748 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H4P51_RS10890 2253749..2253940 - 192 WP_000457842.1 YebW family protein -
H4P51_RS10895 2254045..2254281 - 237 WP_001295499.1 DUF1480 family protein -
H4P51_RS10900 2254399..2255838 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T169787 NZ_CP060057:2252854-2252957 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT169787 NZ_CP060057:c2252995-2252724 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References