Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 555200..555737 Replicon plasmid plas1
Accession NZ_CP060053
Organism Croceicoccus marinus strain OT19

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H4O24_RS17295 Protein ID WP_185885768.1
Coordinates 555447..555737 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag H4O24_RS17290 Protein ID WP_185885767.1
Coordinates 555200..555454 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4O24_RS17260 550357..550518 - 162 WP_083988080.1 hypothetical protein -
H4O24_RS17265 550677..551795 - 1119 WP_185885762.1 copper resistance protein B -
H4O24_RS17270 551797..553803 - 2007 WP_185885763.1 copper resistance system multicopper oxidase -
H4O24_RS17275 553879..554118 - 240 WP_185885764.1 hypothetical protein -
H4O24_RS17280 554167..554496 - 330 WP_185885765.1 hypothetical protein -
H4O24_RS17285 554738..554977 - 240 WP_185885766.1 hypothetical protein -
H4O24_RS17290 555200..555454 + 255 WP_185885767.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
H4O24_RS17295 555447..555737 + 291 WP_185885768.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H4O24_RS17300 555881..556510 + 630 WP_185885769.1 plasmid pRiA4b ORF-3 family protein -
H4O24_RS17305 556763..557863 + 1101 WP_185885770.1 nitronate monooxygenase -
H4O24_RS17310 558011..558575 + 565 Protein_482 IS110 family transposase -
H4O24_RS17315 558911..559174 - 264 WP_185885771.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1029490 1029490


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(7-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10954.54 Da        Isoelectric Point: 8.9717

>T169778 WP_185885768.1 NZ_CP060053:555447-555737 [Croceicoccus marinus]
MPDLQISRRAASDLAEIADYTIAEFGIEQARKYRDLLQSCFQSLLENPGLGRSAEELAPGLRRIRQQAHVIFYRPTGSAI
LIVRVLHHSRDFGRYL

Download         Length: 291 bp

>T169778 NZ_CP076693:2288864-2289238 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCAGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9343.24 Da        Isoelectric Point: 4.4432

>AT169778 WP_185885767.1 NZ_CP060053:555200-555454 [Croceicoccus marinus]
MATIRKTITLSDSQDAWIKAQIARGAFTNDSEYIRDLVRRDQEGQNSLAELRQAIAEGLESGVSDQSLDDIWTTAEKRSR
SADA

Download         Length: 255 bp

>AT169778 NZ_CP076693:2288407-2288775 [Escherichia coli]
GTGTCAGACAAACTCCATGAGACAAATTATCCCGACGACCATAACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References