Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1937099..1937244 | Replicon | chromosome |
| Accession | NZ_CP060049 | ||
| Organism | Klebsiella pneumoniae strain NICU_2_P7 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1937135..1937237 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1937099..1937244 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4W47_RS09325 | 1932229..1934289 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| E4W47_RS09330 | 1934293..1934952 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| E4W47_RS09335 | 1935031..1935261 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| E4W47_RS09340 | 1935374..1935748 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| E4W47_RS09345 | 1935752..1936621 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| E4W47_RS09350 | 1936638..1936976 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1937099..1937244 | - | 146 | - | - | Antitoxin |
| - | 1937135..1937237 | + | 103 | - | - | Toxin |
| E4W47_RS09355 | 1937612..1937755 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| E4W47_RS09360 | 1937860..1938828 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| E4W47_RS09365 | 1938985..1939638 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| E4W47_RS09370 | 1939635..1939826 | - | 192 | WP_002911395.1 | YebW family protein | - |
| E4W47_RS09375 | 1939924..1940163 | - | 240 | WP_002911393.1 | YebV family protein | - |
| E4W47_RS09380 | 1940279..1941712 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T169759 NZ_CP060049:1937135-1937237 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT169759 NZ_CP060049:c1937244-1937099 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
