Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 887451..888103 Replicon chromosome
Accession NZ_CP060040
Organism Burkholderia cenocepacia strain PS27

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SY91_RS20500 Protein ID WP_185921326.1
Coordinates 887451..887744 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SY91_RS20505 Protein ID WP_023476008.1
Coordinates 887747..888103 (+) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SY91_RS20475 883340..883780 - 441 WP_034174798.1 hypothetical protein -
SY91_RS20480 884105..884407 + 303 WP_185921324.1 hypothetical protein -
SY91_RS20485 884446..884649 + 204 WP_023476011.1 ogr/Delta-like zinc finger family protein -
SY91_RS20490 884735..885394 + 660 WP_043887438.1 AAA family ATPase -
SY91_RS20495 885879..887009 + 1131 WP_185921325.1 hypothetical protein -
SY91_RS20500 887451..887744 + 294 WP_185921326.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SY91_RS20505 887747..888103 + 357 WP_023476008.1 putative addiction module antidote protein Antitoxin
SY91_RS20510 888147..889199 - 1053 WP_023476007.1 phage portal protein -
SY91_RS20515 889196..889570 - 375 WP_185921405.1 terminase -
SY91_RS20520 889550..889984 + 435 Protein_785 phage late control D family protein -
SY91_RS20525 890260..891423 + 1164 WP_185921327.1 hypothetical protein -
SY91_RS20530 891494..892522 + 1029 WP_185921328.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 884446..892872 8426


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(6-94)

Antitoxin

Uncharacterized protein HI1420

(16-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10663.37 Da        Isoelectric Point: 9.9712

>T169735 WP_185921326.1 NZ_CP060040:887451-887744 [Burkholderia cenocepacia]
MFKVLTPQFDSWLDGLRDPVGSAAISLRIERAKLGNLGQWRAVGDGVNEMKIDVGPGYRAYFVRRGKIIVVVLCGGDKST
QKKDIKTAKQIAGELED

Download         Length: 294 bp

>T169735 NZ_CP076687:c2249852-2249598 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAGCAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAACTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCTTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 12425.19 Da        Isoelectric Point: 7.3180

>AT169735 WP_023476008.1 NZ_CP060040:887747-888103 [Burkholderia cenocepacia]
MKISELAEFDGSKYLKDEETIRHYLAQAFEDGDPRLIQAALGNVAKARGMTALARESGVKREALYRALSEGGNAEFATIM
KVVGALGLHLTVAPAQPAAEAAPVPAPTPTRARAAAHA

Download         Length: 357 bp

>AT169735 NZ_CP076687:c2250100-2249849 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGACAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References