Detailed information of TA system TA169722

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 1618284..1618937
• Replicon: chromosome
• Accession: NZ_CP060029
• Organism: Acinetobacter baumannii strain AbCTX1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: H4B47_RS07955
• Protein ID: WP_000607070.1
• Coordinates: 1618548..1618937 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: H4B47_RS07950
• Protein ID: WP_001288210.1
• Coordinates: 1618284..1618541 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H4B47_RS07930	1613800..1614807	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
H4B47_RS07935	1614826..1615203	+	378	WP_001216380.1	50S ribosomal protein L17	-
H4B47_RS07940	1615384..1616874	+	1491	WP_000415133.1	NAD(P)/FAD-dependent oxidoreductase	-
H4B47_RS07945	1616924..1618096	-	1173	WP_001190546.1	acyl-CoA dehydrogenase family protein	-
H4B47_RS07950	1618284..1618541	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
H4B47_RS07955	1618548..1618937	+	390	WP_000607070.1	hypothetical protein	Toxin
H4B47_RS07960	1619708..1620793	+	1086	WP_000049107.1	hypothetical protein	-
H4B47_RS07965	1620871..1621437	+	567	WP_000651536.1	rhombosortase	-
H4B47_RS07970	1621625..1623820	+	2196	WP_001158905.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15708.02 Da
• Isoelectric Point: 10.3599

>T169722 WP_000607070.1 NZ_CP060029:1618548-1618937 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T169722 NZ_CP076679:c4379456-4379073 [Rhodopseudomonas palustris]
ATGCGACCGCGACTTGTAAGCGGCGAAAAGCCGCTCCACTGGGTGGGCTCATCGAAAGACGACCTTTGCGCCTTTCCGTT
GCCGGTGCAGCGTGAGATCGGCAATGCGTTGGGATTGGCGCAGTTCGGCGGCAAGCATCCGCGTGCCAAGCCCTGGAAGG
GCGAGGGGCCGGGCGTGTTCGAAATGGTCGACGATTTCGACGGCGATACCTACCGAGCGGTCTATACGGTGCGCTTCCGG
CACGCGGTCTACGTGCTGCACGCATTCCAAAAGAAGTCGCCGCGCGGCATCCGAACCGCGCGCGGCGATATCGAACTCAT
TGCGCGGCGGCTGAAGCTCGCCCGACAGGATGACGAGGCCCGTGATGGCGAGAACGACCGCTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT169722 WP_001288210.1 NZ_CP060029:1618284-1618541 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT169722 NZ_CP076679:c4379065-4378742 [Rhodopseudomonas palustris]
ATGGCAGCCGAGATCACCCGCGGCAGCGGCAATGTGTTTGCGGACCTGGGCATGGCCGACGCGGAGGAGAGGCAGACCAA
GCTCAGGCTCACCTACGCTCTGAACGCGGTGATCGACCGGGCTCGCCTGAGCCAAGCCGCCGCCGCCGAGCGGCTCGGGA
TCAACCAGCCCAAGGTCTCTGCCCTGCGCAATTACAAACTAGAAGGCTTTTCGGTCGAGCGGCTGATGACGTTGCTCAAC
GCGCTCGATCAGGACATCGAAATTGTCATCCGCAAAAAGCCACGCTCGCGCGCGGCGGCGCGGATCAGCGTAGTGGCGGC
GTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7