Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2037132..2037697 Replicon chromosome
Accession NZ_CP060028
Organism Pseudoxanthomonas mexicana strain GTZY

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H4W19_RS09670 Protein ID WP_185894128.1
Coordinates 2037132..2037452 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H4W19_RS09675 Protein ID WP_185894129.1
Coordinates 2037440..2037697 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4W19_RS09650 2033763..2034476 + 714 WP_162108432.1 phosphoadenylyl-sulfate reductase -
H4W19_RS09655 2034617..2035879 + 1263 WP_185897074.1 histidine kinase -
H4W19_RS09660 2035876..2036646 + 771 WP_185894126.1 LytTR family DNA-binding domain-containing protein -
H4W19_RS09665 2036757..2037125 + 369 WP_185894127.1 hypothetical protein -
H4W19_RS09670 2037132..2037452 - 321 WP_185894128.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H4W19_RS09675 2037440..2037697 - 258 WP_185894129.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H4W19_RS09680 2037716..2038144 - 429 WP_185894130.1 DUF2809 domain-containing protein -
H4W19_RS09685 2038090..2038437 - 348 WP_185894131.1 hypothetical protein -
H4W19_RS09690 2038526..2039509 - 984 WP_162108437.1 LysR family transcriptional regulator -
H4W19_RS09695 2039682..2041136 + 1455 WP_185894132.1 siroheme synthase CysG -
H4W19_RS09700 2041158..2042132 + 975 WP_162108439.1 cysteine synthase A -
H4W19_RS09705 2042142..2042606 - 465 WP_185894133.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12132.12 Da        Isoelectric Point: 10.0893

>T169720 WP_185894128.1 NZ_CP060028:c2037452-2037132 [Pseudoxanthomonas mexicana]
MVEIVWSEPALADLDAIADYIALDNRAAAIELVRRVFAHVDHLADHPDSGSRPPELKRGRYRQIVEPPCRVFYRSEPGRV
LILHVMRSERLLRPGMLQVRKPGKAR

Download         Length: 321 bp

>T169720 NZ_CP076679:c1815377-1815081 [Rhodopseudomonas palustris]
ATGATTGACGTTCGCGAAACAGCGGATTTCACGAACTGGCTCGCCGCCTTGAGCGACCTGCGCGCCCGTCTGCAGATCGT
TCGCCGGATCGACCGGATTGCCGCGGGAAACTTCGGTGATGCCAAATCGGTTGGTGGCGCGGTGAAGGAGCTTCGGATCG
ACTACGGACCGGGCTACCGAGTTTACTACACGCGGCGCGGCGACACCGTCGTCATCCTGCTCTGCGGCGGCGACAAGCGG
ACGCAAAGCAAGGACATCCGGAAGGCTAAGGAAATTGCAGAGGCGTTGGAGGACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9611.02 Da        Isoelectric Point: 6.4681

>AT169720 WP_185894129.1 NZ_CP060028:c2037697-2037440 [Pseudoxanthomonas mexicana]
MRTELVTTLKRQATDLLADVERDREPILITQHGLPSAYLVDVETYETLLSRMAVLEGIARGEQAVAEGRAVTHPQARDRL
ARWLK

Download         Length: 258 bp

>AT169720 NZ_CP076679:c1815078-1814761 [Rhodopseudomonas palustris]
ATGAAGGTCAGCAAACTGAAGAAGTTCAACGCGGCCGAACACCTTCGTACACCGGAAGCACGCGCGGAGTATCTGAACAT
CGTTCTCGCCGACGGCGACCCCAACGAAGTGCGTGACGCACTCAATCTCGTCGCTCGCGCGCAGGGCATGAGCGCGATCG
CCAAGGCCGCTGGCGTCACCAGAGAGGGACTCTACAAGACGCTCGGTGAGAACGGTAACCCCGAGTTCGCAACCATCCTC
CGGGTGTTCGGCGCCATGGGATTCCGGTTGACGGCAGAACTGGCCAAAAACAAGCCGAGAAGGAAAGCAGTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References