Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/-
Location 498225..498878 Replicon chromosome
Accession NZ_CP060013
Organism Acinetobacter baumannii strain TP3

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag H5028_RS02405 Protein ID WP_000607077.1
Coordinates 498489..498878 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag H5028_RS02400 Protein ID WP_001288210.1
Coordinates 498225..498482 (+) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5028_RS02380 493741..494748 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
H5028_RS02385 494767..495144 + 378 WP_001216380.1 50S ribosomal protein L17 -
H5028_RS02390 495326..496816 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
H5028_RS02395 496865..498037 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
H5028_RS02400 498225..498482 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
H5028_RS02405 498489..498878 + 390 WP_000607077.1 membrane protein Toxin
H5028_RS02410 499648..500733 + 1086 WP_000049106.1 hypothetical protein -
H5028_RS02415 500811..501377 + 567 WP_000651538.1 rhombosortase -
H5028_RS02420 501565..503760 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(10-82)


Sequences


Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T169690 WP_000607077.1 NZ_CP060013:498489-498878 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T169690 NZ_CP076656:c2067090-2066764 [Pasteurella sp. XG20]
ATGGACAGAGTCCGATTTAATCTTACGGAAGATAGCTTCCAAGACAAGTATCTGTATGAGTATTTTTTATATGGAAGTAA
GCATAAAAATATTCCAAGTGATATAGAAAATACGCTAGCGCATAAATTAGATATGTTAGATAGCGCAAATACTTTGAGCG
ATTTGCGAAGTCAACCAGGTAATAAATTGGAAAAATTGGAGCCTAAAACGAGTGGGCTATATTCTATCAGAGTGAATGTG
AAATATCGTTTAATATTTAAATATAAAGAAAGTAATTTTCCAAAAATAACAGAGTTGAGATTAGATAAACATCAATATAG
ATTATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT169690 WP_001288210.1 NZ_CP060013:498225-498482 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT169690 NZ_CP076656:c2066656-2066330 [Pasteurella sp. XG20]
ATGAGTAGAGTACAAAGAAAGCCATCAACAGTGGGTGATATTTTATTAGATGAATATTTAGTTCCACTAAATTTGAAAAT
TGCAGATTTAGCTACAATGTTAGATGTTCATCGTAATACAGCGAGTGCACTCGTTAATAATAATACTAAATTGTCTTTAG
AAATGGCACTGAAACTAGCAAAACTATTTAATACAAGTCCTGAGTTTTGGTTAAATTTACAAATGAAATTAGACTTATGG
GAAATTGAAAACAATGCTAGGTTTCAAGAAAGTTTAAAGAAAATTTCGTCTATTGATCAGCATAATCTGTTAGAAAAAAT
CGCTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References