Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4353865..4354406 Replicon chromosome
Accession NZ_CP060009
Organism Pseudomonas sediminis strain B10D7D

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HNQ25_RS20490 Protein ID WP_179545816.1
Coordinates 4354110..4354406 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HNQ25_RS20485 Protein ID WP_179545815.1
Coordinates 4353865..4354122 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HNQ25_RS20455 4349438..4349932 + 495 WP_179545812.1 GNAT family N-acetyltransferase -
HNQ25_RS20460 4350008..4350286 - 279 WP_125881680.1 DUF465 domain-containing protein -
HNQ25_RS20465 4350355..4350603 - 249 WP_099522588.1 YdcH family protein -
HNQ25_RS20470 4350800..4351825 + 1026 WP_106732618.1 DUF21 domain-containing protein -
HNQ25_RS20475 4351826..4352602 - 777 WP_179545813.1 ferredoxin--NADP reductase -
HNQ25_RS20480 4352672..4353796 + 1125 WP_179545814.1 class I SAM-dependent methyltransferase -
HNQ25_RS20485 4353865..4354122 + 258 WP_179545815.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HNQ25_RS20490 4354110..4354406 + 297 WP_179545816.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HNQ25_RS20495 4354410..4355729 - 1320 WP_179545817.1 TldD/PmbA family protein -
HNQ25_RS20500 4355729..4357171 - 1443 WP_179545818.1 TldD/PmbA family protein -
HNQ25_RS20505 4357242..4357391 - 150 WP_179546266.1 DUF2474 domain-containing protein -
HNQ25_RS20510 4357402..4358409 - 1008 WP_106732607.1 cytochrome d ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11407.20 Da        Isoelectric Point: 5.1356

>T169687 WP_179545816.1 NZ_CP060009:4354110-4354406 [Pseudomonas sediminis]
MAEIVWTNSAIEQLDDLAQYIALDKPDAARALVRRAVETVSRLADFPLSGRVPDELPHSVYREIVVPPCRIFYRYTDTTV
FIIYIMREERVLRAHMLE

Download         Length: 297 bp

>T169687 NZ_CP076655:72381-72668 [Escherichia coli]
ATGACTTATACAGTAAAATTCAGGGATGATGCGCTCAAAGAATGGCTGAAACTGGATAAATCCATTCAACAGCAGTTTGC
GAAAAAACTAAAGAAATGCAGCGAAAATCCTCATATTCCTTCCGCAAAACTGCGTGGATTAAAAGACTGCTACAAAATCA
AACTTCGCGCATCGGGGTTTCGTCTGGTCTATCAGGTTATTGATGACATGCTAATTATTGCGGTTGTCGCGGTAGGTAAA
CGTGAACGTAGTAACGTTTATAATCTCGCCAGTGAGAGAATGAGATAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9732.32 Da        Isoelectric Point: 7.2775

>AT169687 WP_179545815.1 NZ_CP060009:4353865-4354122 [Pseudomonas sediminis]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQKRLALLDALARGERAVIEGCTVNHEQAKERL
SKWLK

Download         Length: 258 bp

>AT169687 NZ_CP076655:72133-72384 [Escherichia coli]
ATGCCTAACATCATTCTGTCTGACACCAGTGCAAGTGTCAGTGAACTGAAAAAAAATCCTATGGCTACAGTCAGTGCCGG
AGATGGTTATCCTGTCGCCATTCTTAACCGGAATCAGCCGGCATTCTACTGTGTGCCTGCGGAACTCTATGAAAGGATGC
TTGATGCGCTGGATGACCAGGAACTGGTGAAACTGGTTACTGAACGCAGCAATCAGCCACTGCATGATGTGGACCTGGAC
AGTTATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References