Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1674418..1675618 Replicon chromosome
Accession NZ_CP060009
Organism Pseudomonas sediminis strain B10D7D

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HNQ25_RS07970 Protein ID WP_179544245.1
Coordinates 1674866..1675618 (+) Length 251 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HNQ25_RS07965 Protein ID WP_099525737.1
Coordinates 1674418..1674789 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HNQ25_RS07945 1670794..1671120 + 327 WP_037003146.1 Grx4 family monothiol glutaredoxin -
HNQ25_RS07950 1671184..1671522 - 339 WP_179544242.1 YdbL family protein -
HNQ25_RS07955 1671534..1671725 - 192 WP_179544243.1 YnbE family lipoprotein -
HNQ25_RS07960 1671730..1674285 - 2556 WP_179544244.1 YdbH domain-containing protein -
HNQ25_RS07965 1674418..1674789 + 372 WP_099525737.1 DUF2384 domain-containing protein Antitoxin
HNQ25_RS07970 1674866..1675618 + 753 WP_179544245.1 RES family NAD+ phosphorylase Toxin
HNQ25_RS07975 1676058..1676309 + 252 WP_013716752.1 sel1 repeat family protein -
HNQ25_RS07980 1676489..1677850 + 1362 WP_179546193.1 DNA recombination protein RmuC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(63-207)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(8-68)


Sequences

Toxin        


Download         Length: 251 a.a.        Molecular weight: 28348.35 Da        Isoelectric Point: 7.2067

>T169685 WP_179544245.1 NZ_CP060009:1674866-1675618 [Pseudomonas sediminis]
MDIWQLCDGERQVRPLRGKLLRMVESQAQVATLQLVDTLAEQALLEELLENSKPPLPEATEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAAQRLETAMAEAAYYRFVLWNGMDTAPPSGRILSEHSTFEARYRVERGIQLHKPPFEGHGVLLAHPSD
YSVPQRLGAAMRAAGIQAFEYRSARCPDGGSNVALYVPAAFAEKRPRNLTAWLCETTGEYVAFKHAQTPDQPRLFHWEQF
LVQGQLPHPA

Download         Length: 753 bp

>T169685 NZ_CP076655:39218-39523 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGTTGTCAGATAAGGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAGGAAGTG
GCTGATCTCAGCCACCGAGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13683.73 Da        Isoelectric Point: 10.6605

>AT169685 WP_099525737.1 NZ_CP060009:1674418-1674789 [Pseudomonas sediminis]
MSAVTRSQPDADAVLAKALLNTREHLGLTQQELADIVGVHRSAISRWNEQGGLRPQSKTGELALLLIRAYRALFALFGGN
QQDMRHFLRTENRHLAGVPLQQMSQVQGLVRVVEYLDAIRGKV

Download         Length: 372 bp

>AT169685 NZ_CP076655:38998-39216 [Escherichia coli]
ATGAAGCAGCGCATTACAGTCACCGTCGACAGTGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGGCT
GGTAAGCACCACCCTGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCAGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGACGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References